文献类型： 外文期刊
作者： Chen, Xi 1 ; Yang, Jin-Xian 1 ; Li, Ying-Ying 1 ; Song, Tie-Ying 1 ; Ge, Jun-Qing 1 ;
作者机构： 1.Fujian Acad Agr Sci, Inst Biotechnol, 247 Wusi Rd, Fuzhou 350003, Peoples R China
关键词： Anguillid herpesvirus; ORF95; Late gene; Subcellular localization; Envelope protein
期刊名称：VIRUS GENES （ 影响因子：1.991； 五年影响因子：1.776 ）
ISSN： 0920-8569
年卷期：
页码：
收录情况： SCI
摘要： Anguillid herpesvirus 1 (AngHV) is one of the vital pathogenic agents found in the wild and cultured eel populations, which has brought significant losses to eel culture industry in China. In this study, AngHV ORF95 was characterized. Bioinformatics analysis showed that ORF95 putatively encodes a structural protein that is homologous to hemagglutinin-esterase (HE) protein of infectious salmon anemia virus (ISAV). Temporal transcription and expression analysis indicated that ORF95 is a viral late gene. Subcellular localization analysis revealed that ORF95 was predominantly localized in the cytoplasm. Further, western blot analysis indicated that ORF95 is a structural protein of virion envelope. These results provide a novel basis to make further efforts to clarify the function of ORF95 in the process of AngHV infection and the possibility to use ORF95 as antigen to develop AngHV subunit vaccine.
- 相关文献
作者其他论文 更多>>
-
Isolation, Identification, and Pathogenicity Characterization of a Largemouth Bass Ranavirus from Fujian, China
作者：Yang, Jin-Xian;Chen, Xi;Chen, Hua;Ge, Jun-Qing
关键词：Micropeterus salmoides; Ulcerative disease; Ranavirus; Isolation; Pathogenicity
-
Immune responses and protective efficacy of American eel (Anguilla rostrata) immunized with a formalin-inactivated vaccine against Anguillid herpesvirus
作者：Zhang, Li -Juan;Chen, Qiang;Yang, Jin-Xian;Ge, Jun-Qing;Ge, Jun-Qing
关键词：Anguillid herpesvirus; Anguilla rostrata; Formalin-inactivated vaccine; Immune response; Protective efficacy
-
Development and application of a recombinase-aided amplification combined with a lateral flow dipstick assay for rapid visual detection of anguillid herpesvirus 1
作者：Chen, Xi;Chen, Hua;Ge, Jun-Qing;Ge, Jun-Qing
关键词：anguillid herpesvirus 1; eel; lateral flow dipstick assay; on-site diagnosis; recombinase-aided amplification
-
Metagenomic analysis fecal microbiota of dysentery-like diarrhoea in a pig farm using next-generation sequencing
作者：Chen, Xi;Li, Ying-Ying;Song, Tie-Ying;Ge, Jun-Qing;Guo, Qing
关键词：dysentery-like diarrhea; metagenomic analysis; fecal microbiota; carbohydrate-active enzyme; antibiotic resistance; virulence factor
-
Proteomic Profiling Skin Mucus of European Eel Anguilla anguilla Infected with Anguillid Herpesvirus
作者：Li, Ying-Ying;Yang, Jin-Xian;Chen, Xi;Chen, Qiang;Song, Tie-Ying;Ge, Jun-Qing
关键词：Anguilla anguilla; Anguillid herpesvirus; TMT-labelled; proteomic; skin mucus
-
Expression Profiles of Zebrafish (Danio rerio) Lysozymes and Preparation of c-Type Lysozyme with High Bacteriolytic Activity against Vibrio vulnificus
作者：Chen, Hua;Chen, Xi;Song, Tie-Ying;Ge, Jun-Qing;Chen, Hua
关键词：lysozyme; zebrafish; expression; Vibrio vulnificus; antimicrobial activity
-
Bombyx mori Nucleopolyhedrovirus p26 Is Associated with Viral Late Stage Replication
作者：Ge, Jun-Qing;Chen, Xi;Chen, Hua;Wang, Zhu-Hong;Huang, Jian
关键词：BmNPV; p26; expression; subcellular localization; knockdown; replication
