The Dynamics of Gene Expression Unraveling the Immune Response of Macrobrachium rosenbergii Infected by Aeromonas veronii
文献类型： 外文期刊
作者： Peng, Xin 1 ; Lan, Xuan 1 ; Zhong, Zhenxiao 1 ; Tu, Haihui 1 ; Yao, Xinyi 1 ; Tang, Qiongying 2 ; Xia, Zhenglong 3 ; Yang, Guoliang 1 ; Yi, Shaokui 1 ;
作者机构： 1.Huzhou Univ, Chinese Acad Fishery Sci, Key Lab Aquat Anim Genet Breeding & Nutr, Huzhou 313000, Peoples R China
2.Huzhou Univ, Zhejiang Prov Key Lab Aquat Resources Conservat &, Huzhou 313000, Peoples R China
3.Jiangsu Shufeng Prawn Breeding Co Ltd, Gaoyou 225654, Peoples R China
关键词： transcriptome; differentially expressed genes; Macrobrachium rosenbergii; Aeromonas veronii
期刊名称：GENES （ 影响因子：3.5； 五年影响因子：3.9 ）
ISSN：
年卷期： 2023 年 14 卷 7 期
页码：
收录情况： SCI
摘要： To further investigate the immune response of Macrobrachium rosenbergii against Aeromonas veronii, comparative transcriptomic analyses of the M. rosenbergii hepatopancreas were conducted on challenge and control groups at 6, 12, and 24 h post-infection (hpi), independently. A total of 51,707 high-quality unigenes were collected from the RNA-seq data, and 8060 differentially expressed genes (DEGs) were discovered through paired comparisons. Among the three comparison groups, a KEGG pathway enrichment analysis showed that 173 immune-related DEGs were considerably clustered into 28 immune-related pathways, including the lysosome, the phagosome, etc. Moreover, the expression levels of the four key immune-related genes (TOLL, PAK1, GSK3 & beta;, and IKK & alpha;) were evaluated at various stages following post-infection in the hepatopancreas, hemolymph, and gills. Both PAK1 and GSK3 & beta; genes were highly up-regulated in all three tissues at 6 hpi with A. veronii; TOLL was up-regulated in the hepatopancreas and hemolymph but down-regulated in the gill at 6 hpi, and IKK & alpha; was up-regulated in hemolymph and gill, but down-regulated in the hepatopancreas at 6 hpi. These findings lay the groundwork for understanding the immune mechanism of M. rosenbergii after contracting A. veronii.
- 相关文献
作者其他论文 更多>>
-
Simultaneous detection of five shrimp pathogens using a single-tube EvaGreen real-time PCR assay with differential melting temperature
作者：Lou, Haoyu;Li, Xuan;Wang, Guohao;Zhang, Kaisong;Wang, Kejun;Huang, Jie;Dong, Xuan;Lou, Haoyu;Tang, Qiongying;Yang, Guoliang;Jia, Peng;Xiong, Jinbo
关键词：shrimp pathogens; EvaGreen; multiplex detection; melting temperature
-
Infection with infectious precocious virus (IPV) suppresses infection with decapod iridescent virus 1 (DIV1) in Macrobrachium rosenbergii
作者：Lou, Haoyu;Tang, Qiongying;Yang, Guoliang;Lou, Haoyu;Wang, Guohao;Li, Xuan;Zhou, Chengyan;Guo, Xiaomeng;Wang, Liying;Dong, Xuan;Huang, Jie;Wang, Guohao;Zhou, Chengyan;Guo, Xiaomeng;Huang, Jie;Li, Xuan;Yang, Guoliang
关键词：Macrobrachium rosenbergii; Co-infection; DIV1; IPV
-
Coinfection with infectious precocity virus and Decapod iridescent virus 1 in farmed giant freshwater prawn ( Macrobrachium rosenbergii )
作者：Wang, Guohao;Guo, Xiaomeng;Zhou, Chengyan;Huang, Jie;Yao, Jiayun;Wang, Guohao;Guo, Xiaomeng;Zhou, Chengyan;Lou, Haoyu;Li, Xuan;Dong, Xuan;Huang, Jie;Li, Xuan;Dong, Xuan;Dong, Xuan;Yang, Guoliang;Huang, Jie;Huang, Jie;Yao, Jiayun;Dong, Xuan
关键词：IPV; DIV1; Coinfection; Macrobrachium rosenbergii
-
Transcriptome analysis of the gonad reveals growth differences between large, medium and small individuals in a pure family of Macrobrachium rosenbergii
作者：Liu, Peimin;Zhao, Xiuxin;Tang, Qiongying;Li, Jingfen;Dong, Haiyan;Yang, Guoliang;Yi, Shaokui;Gao, Quanxin;Xia, Zhenglong;Yang, Guoliang;Yi, Shaokui;Gao, Quanxin
关键词：Macrobrachium Rosenbergii; Gonad; RNA -sequencing; Growth; Differentially expressed genes
-
Isolation, identification, and evaluation of intestinal bacteria in Macrobrachium rosenbergii
作者：Zhao, Xiuxin;Luo, Jinping;Liu, Peimin;Huang, Hao;Cheng, Zhenheng;Peng, Xin;Tang, Qiongying;Yang, Guoliang;Yi, Shaokui;Gao, Quanxin;Zhao, Xiuxin;Luo, Jinping;Liu, Peimin;Huang, Hao;Cheng, Zhenheng;Peng, Xin;Tang, Qiongying;Yang, Guoliang;Yi, Shaokui;Gao, Quanxin;Zhao, Xiuxin;Luo, Jinping;Liu, Peimin;Huang, Hao;Cheng, Zhenheng;Peng, Xin;Tang, Qiongying;Yang, Guoliang;Yi, Shaokui;Gao, Quanxin;Yang, Guoliang;Yi, Shaokui;Gao, Quanxin
关键词：Macrobrachium rosenbergii; intestinal bacteria; probiotic; Lactococcus garvieae
-
Integrated Transcriptomic and Metabolomic Analyses Reveal Low-Temperature Tolerance Mechanism in Giant Freshwater Prawn Macrobrachium rosenbergii
作者：Tu, Haihui;Peng, Xin;Yao, Xinyi;Tang, Qiongying;Li, Jingfen;Yang, Guoliang;Yi, Shaokui;Xia, Zhenglong;Yang, Guoliang
关键词：low-temperature tolerance; gene regulation; metabolite; lipid metabolism; energy metabolism
-
Alterations of the Gut Microbiota and Metabolomics Associated with the Different Growth Performances of Macrobrachium rosenbergii Families
作者：Lan, Xuan;Peng, Xin;Du, Tingting;Gao, Quanxin;Tang, Qiongying;Yi, Shaokui;Yang, Guoliang;Xia, Zhenglong;Yang, Guoliang
关键词：growth performance; gut bacteria; metabolism; LC-MS
