Associated analysis of single nucleotide polymorphisms of IGF2 gene's exon 8 with growth traits in Wuzhishan pig
文献类型： 外文期刊
作者： Hou, Guanyu 2 ; Wang, Dongjin 2 ; Guan, Song 2 ; Zeng, Hongpu 1 ; Huang, Xianzhou 1 ; Ma, Yuehui 1 ;
作者机构： 1.Chinese Acad Agr Sci, Inst Anim Sci, Beijing 100094, Peoples R China
2.CATAS, Trop Crops Genet Resources Inst, Danzhou 571737, Hainan, Peoples R China
关键词： Hardy-Weinberg equilibrium;growth trait;chest girth;polymorphism information content
期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.316； 五年影响因子：2.357 ）
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收录情况： SCI
摘要： A new SNP located in IGF-2 gene of Wuzhishan pig was detected while a C -> T silent mutation at position 17 of exon 8 was detected by Single-Strand Conformational Polymorphism (SSCP). The value of polymorphism information content (PIC) indicated that this locus had intermediate polymorphism information content (0.25 < PIC < 0.5). The results of the fitness of Hardy-Weinberg equilibrium was in disequilibrium (P < 0.01). SAS analysis together with the multiple comparisons between polymorphisms and growth traits showed that: the differences of carcass weight (P = 0.024), withers height (P = 0.037) and chest girth (P = 0.025) in 10-month-old generation group were very remarkable.
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