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Preparation and pH Controlled Release of Fe3O4/Anthocyanin Magnetic Biocomposites

文献类型： 外文期刊

作者： Jiang, Xizhi 1 ; Guan, Qingbao 4 ; Feng, Min 2 ; Wang, Mengyang 2 ; Yan, Nina 2 ; Wang, Min 2 ; Xu, Lei 2 ; Gui, Zhongzhe 1 ;

作者机构： 1.Jiangsu Univ Sci & Technol, Sch Biotechnol, Zhenjiang 212018, Jiangsu, Peoples R China

2.Jiangsu Acad Agr Sci, Inst Agr Facil & Equipment, Nanjing 210014, Peoples R China

3.Minist Agr & Rural Affairs, Key Lab Protected Agr Engn Middle & Lower Reaches, Nanjing 210014, Peoples R China

4.Donghua Univ, Coll Mat Sci & Engn, Int Joint Lab Adv Fiber & Low Dimens Mat, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China

关键词： magnetic biocomposite; anthocyanin; Fe3O4; storage; release

期刊名称：POLYMERS （ 影响因子：4.329； 五年影响因子：4.493 ）

ISSN：

年卷期： 2019 年 11 卷 12 期

页码：

收录情况： SCI

摘要： Anthocyanins are a class of antioxidants extracted from plants, with a variety of biochemical and pharmacological properties. However, the wide and effective applications of anthocyanins have been limited by their relatively low stability and bioavailability. In order to expand the application of anthocyanins, Fe3O4/anthocyanin magnetic biocomposite was fabricated for the storage and release of anthocyanin in this work. The magnetic biocomposite of Fe3O4 magnetic nanoparticle-loaded anthocyanin was prepared through physical intermolecular adsorption or covalent cross-linking. Scanning electron microscopy (SEM), Dynamic light scattering (DLS), Fourier-transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD) and thermal analysis were used to characterize the biocomposite. In addition, the anthocyanin releasing experiments were performed. The optimized condition for the Fe3O4/anthocyanin magnetic biocomposite preparation was determined to be at 60 degrees C for 20 h in weak alkaline solution. The smooth surface of biocomposite from SEM suggested that anthocyanin was coated on the surface of the Fe3O4 particles successfully. The average size of the Fe3O4/anthocyanin magnetic biocomposite was about 222 nm. Under acidic conditions, the magnetic biocomposite solids could be repeatable released anthocyanin, with the same chemical structure as the anthocyanin before compounding. Therefore, anthocyanin can be effectively adsorbed and released by this magnetic biocomposite. Overall, this work shows that Fe3O4/anthocyanin magnetic biocomposite has great potential for future applications as a drug storage and delivery nanoplatform that is adaptable to medical, food and sensing.

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