Phenylalanine Plays Important Roles in Regulating the Capacity of Intestinal Immunity, Antioxidants and Apoptosis in Largemouth Bass (Micropterus salmoides)
文献类型： 外文期刊
作者： Yi, Changguo 1 ; Liang, Hualiang 1 ; Huang, Dongyu 1 ; Yu, Heng 1 ; Xue, Chunyu 1 ; Gu, Jiaze 1 ; Chen, Xiaoru 3 ; Wang, Yongli 3 ; Ren, Mingchun 1 ; Zhang, Lu 3 ;
作者机构： 1.Nanjing Agr Univ, Wuxi Fisheries Coll, Wuxi 214081, Peoples R China
2.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr & Rural Affairs, Key Lab Integrated Rice Fish Farming Ecol, Wuxi 214081, Peoples R China
3.Tongwei Agr Dev Co Ltd, Minist Agr & Rural Affairs, Key Lab Nutr & Hlth Culture Aquat Livestock & Poul, Hlth Aquaculture Key Lab Sichuan Prov, Chengdu 610093, Peoples R China
关键词： dietary phenylalanine level; largemouth bass; immunity; antioxidants; apoptosis
期刊名称：ANIMALS （ 影响因子：3.0； 五年影响因子：3.2 ）
ISSN： 2076-2615
年卷期： 2023 年 13 卷 18 期
页码：
收录情况： SCI
摘要： This experiment was planned to explore the role of dietary phenylalanine levels in intestinal immunity, antioxidant activity and apoptosis in largemouth bass (Micropterus salmoides). Six iso-nitrogen and iso-energy diets with phenylalanine levels of 1.45% (DPHE1), 1.69% (DPHE2), 1.98% (DPHE3), 2.21% (DPHE4), 2.48% (DPHE5) and 2.76% (DPHE6) were designed. Juvenile largemouth bass were fed the experimental diet for 8 weeks. In this study, the DPHE5 group increased the expression of intestinal antioxidant genes in largemouth bass (p < 0.05), and the increase of antioxidant enzyme activities and content of related substances was most concentrated in the DPHE3 and DPHE4 groups (p < 0.05). The results of plasma biochemistry were similar to that of enzyme activity. The expression of genes related to the TOR signalling pathway mainly increased significantly in the DPHE5 group (p < 0.05). Similarly, the expression of inflammatory factors, as well as apoptotic factors, also showed significant increases in the DPHE5 group (p < 0.05). In conclusion, unbalanced phenylalanine in the diet could lead to a decrease in intestinal immune and antioxidant capacity and also cause a decline in the aggravation of intestinal cell apoptosis.
- 相关文献
作者其他论文 更多>>
-
DL-Methionyl-DL-Methionine/DL-Methionine Supplementation Alleviated the Adverse Effects of Dietary Low Fishmeal Levels on Growth and Intestinal Health of Micropterus salmoides
作者：Yu, Heng;Liang, Hualiang;Ge, Xianping;Xue, Chunyu;Ren, Mingchun;Masagounder, Karthik;Liang, Hualiang;Ge, Xianping;Huang, Dongyu;Ren, Mingchun;He, Juyun
关键词：Micropterus salmoides (M. salmoides); Met-Met; intestinal microbiota; antioxidant capacity; anti-inflammatory
-
Transcriptome-Based Analysis of the Mechanism of Action of Metabolic Disorders Induced by Waterborne Copper Stress in Coilia nasus
作者：Huang, Dongyu;Liang, Hualiang;Ren, Mingchun;Zhang, Lu;Mi, Haifeng;Teng, Tao
关键词：copper stress; metabolic disorders; immune dysregulation; transcriptome analysis; Coilia nasus
-
A delayed and unsynchronized ovary development as revealed by transcriptome of brain and pituitary of Coilia nasus
作者：Yu, Ziyan;Zeng, Yun;Li, Mingyou;Liu, Dong;Yu, Ziyan;Zeng, Yun;Liu, Dong;Gao, Zongshuai;Xu, Gangchun;Ren, Mingchun;Zhu, Yunxia
关键词：Coilia nasus; RNA-seq; gonad; pituitary; weighted gene co-expression analysis
-
Effects of partial substitution of enzymatic hydrolysate of poultry by-product meal for fishmeal on the growth performance, hepatic health, antioxidant capacity, and immunity of juvenile largemouth bass (Micropterus salmoides)
作者：Gu, Jiaze;Zhang, Qile;Liang, Hualiang;Ren, Mingchun;Gu, Jiaze;Zhang, Qile;Huang, Dongyu;Liang, Hualiang;Zhang, Lu;Chen, Xiaoru;Wang, Yongli
关键词：Enzymatic hydrolysate of poultry by-product; Growth performance; Hepatic health; Largemouth bass
-
Excessive Replacement of Fish Meal by Soy Protein Concentrate Resulted in Inhibition of Growth, Nutrient Metabolism, Antioxidant Capacity, Immune Capacity, and Intestinal Development in Juvenile Largemouth Bass (Micropterus salmoides)
作者：Liang, Hualiang;Ren, Mingchun;Yu, Heng;Huang, Dongyu;Zhang, Lu;Mi, Haifeng;Teng, Tao;Yu, Heng;Gu, Jiaze
关键词：replacement of fish meal; soy protein concentrate; nutrition metabolism; antioxidant capacity; immune capacity
-
Establishment of a Coilia nasus Spermatogonial Stem Cell Line Capable of Spermatogenesis In Vitro
作者：Gu, Kaiyan;Zhang, Ya;Zhong, Ying;Kan, Yuting;Jawad, Muhammad;Gui, Lang;Liu, Dong;Li, Mingyou;Gu, Kaiyan;Zhang, Ya;Zhong, Ying;Kan, Yuting;Jawad, Muhammad;Gui, Lang;Liu, Dong;Li, Mingyou;Zhong, Ying;Ren, Mingchun;Xu, Gangchun
关键词：Coilia nasus; spermatogonial stem cell line; spermatids; in vitro spermatogenesis; cryopreservation
-
Sodium chloride alleviates oxidative stress and physiological responses induced by extreme winter cold in genetically improved farmed tilapia (GIFT; Oreochromis niloticus)
作者：Huang, Dongyu;Zhu, Jian;Xu, Gangchun;Ren, Mingchun;Liang, Hualiang;Zhang, Lu;Chen, Xiaoru;Wang, Yongli;Ren, Mingchun;Liang, Hualiang
关键词：Sodium chloride; Oxidative stress; Physiological response; Extreme winter cold; GIFT
