文献类型： 外文期刊

作者： Hu, Guanjing ¹ ; Wang, Zhenyu ¹ ; Tian, Zunzhe ² ; Wang, Kai ⁴ ; Ji, Gaoxiang ¹ ; Wang, Xingxing ¹ ; Zhang, Xianliang ¹ ; Yang, Zhaoen ¹ ; Liu, Xuan ² ; Niu, Ruoyu ¹ ; Zhu, De ² ; Zhang, Yuzhi ¹ ; Duan, Lian ¹ ; Ma, Xueyuan ² ; Xiong, Xianpeng ² ; Kong, Jiali ² ; Zhao, Xianjia ² ; Zhang, Ya ² ; Zhao, Junjie ¹ ; He, Shoupu ¹ ; Grover, Corrinne E. ⁶ ; Su, Junji ⁷ ; Feng, Keyun ⁸ ; Yu, Guangrun ⁴ ; Han, Jinlei ⁴ ; Zang, Xinshan ¹ ; Wu, Zhiqiang ² ; Pan, Weihua ² ; Wendel, Jonathan F. ⁶ ; Ma, Xiongfeng ¹ ;

作者机构： 1.Chinese Acad Agr Sci, Inst Cotton Res, Natl Key Lab Cotton Biobreeding & Integrated Utili, Anyang, Peoples R China

2.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen Branch, Guangdong Lab Lingnan Modern Agr,Minist Agr & Rura, Shenzhen, Peoples R China

3.Zhengzhou Univ, Sch Agr Sci, State Key Lab Cotton Biol, Zhengzhou Res Base, Zhengzhou, Peoples R China

4.Nantong Univ, Sch Life Sci, Nantong, Peoples R China

5.Chinese Acad Agr Sci, Western Res Inst, Changji, Peoples R China

6.Iowa State Univ, Dept Ecol Evolut & Organismal Biol, Ames, IA USA

7.Gansu Agr Univ, Coll Life Sci & Technol, State Key Lab Aridland Crop Sci, Lanzhou, Peoples R China

8.Gansu Acad Agr Sci, Crop Res Inst, Lanzhou, Peoples R China

期刊名称：NATURE GENETICS （ 影响因子：29.0； 五年影响因子：37.4 ）

ISSN： 1061-4036

年卷期： 2025 年 57 卷 4 期

页码：

收录情况： SCI

摘要： Cotton (Gossypium hirsutum L.) is a key allopolyploid crop with global economic importance. Here we present a telomere-to-telomere assembly of the elite variety Zhongmian 113. Leveraging technologies including PacBio HiFi, Oxford Nanopore Technology (ONT) ultralong-read sequencing and Hi-C, our assembly surpasses previous genomes in contiguity and completeness, resolving 26 centromeric and 52 telomeric regions, 5S rDNA clusters and nucleolar organizer regions. A phylogenetically recent centromere repositioning on chromosome D08 was discovered specific to G. hirsutum, involving deactivation of an ancestral centromere and the formation of a unique, satellite repeat-based centromere. Genomic analyses evaluated favorable allele aggregation for key agronomic traits and uncovered an early-maturing haplotype derived from an 11 Mb pericentric inversion that evolved early during G. hirsutum domestication. Our study sheds light on the genomic origins of short-season adaptation, potentially involving introgression of an inversion from primitively domesticated forms, followed by subsequent haplotype differentiation in modern breeding programs.