文献类型： 外文期刊

作者： Li, Yang ¹ ; Zhao, Wei ² ; Li, Qifeng ¹ ; Zhang, Jiayu ¹ ; Yang, Anquan ³ ; Xie, Min ³ ; Xiong, Ranhua ¹ ; Huang, Chaobo ¹ ;

作者机构： 1.Nanjing Forestry Univ, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat Fo, Nanjing, Peoples R China

2.Xinjiang Acad Agr & Reclamat Sci, Anal & Testing Ctr, Shihezi, Peoples R China

3.OSM Biol Co Ltd, Deqing, Peoples R China

关键词： Adsorption; antioxidant; Erigeron breviscapus; extraction; macroporous resin; total flavonoids

期刊名称：PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY （ 影响因子：1.9； 五年影响因子：2.4 ）

ISSN： 1082-6068

年卷期： 2025 年

页码：

收录情况： SCI

摘要： Erigeron breviscapus, a medicinal plant rich in flavonoids with diverse pharmacological properties is an important resource. To maximize the utilization of these valuable bioactive compounds, ultrasound-assisted extraction combined with response surface methodology was used to optimize the extraction conditions for total flavonoids. After comparing six macroporous resins' adsorption and desorption characteristics, AB-8 was selected for enriching total flavonoids, and its adsorption kinetics and thermodynamics were investigated. The following parameters were chosen as optimal for the dynamic adsorption/desorption experiments using an AB-8 filled column: sample loading concentration of 1.14 mg/mL, sample loading flow rate of 2 BV/h, elution solvent of 70% ethanol, desorption flow rate of 1 BV/h, elution solvent volume of 5.5 BV, pH of 2, temperature of 25 degrees C. After enrichment, the concentration of flavonoids was 5.16 times higher than that of crude extract. LC-MS identified 54 flavonoid molecules with excellent antioxidant properties.