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An NBD-NH2 fluorescent probe for bioimaging: existence of a specific detection of ClO-

文献类型: 外文期刊

作者: Yang, Yunxia 1 ; Zhang, Di 2 ; Xu, Mengsheng 1 ; Wang, Jianhong 1 ; Chen, Jipeng 1 ; Wang, Le 1 ;

作者机构: 1.Shanghai Univ Engn Sci, Coll Chem & Chem Engn, Shanghai 201620, Peoples R China

2.Henan Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Henan Cereal Qual & Safety Testing Key Lab, Zhengzhou 450002, Henan, Peoples R China

关键词: NBD-NH2; Fluorescent probe; Hypochlorous

期刊名称:MONATSHEFTE FUR CHEMIE ( 影响因子:1.451; 五年影响因子:1.519 )

ISSN: 0026-9247

年卷期: 2018 年 149 卷 6 期

页码:

收录情况: SCI

摘要: A fluorescent probe 4-amino-7-nitrobenz-2-oxa-1,3-diazole NBD-NH2 for critical sensing hypochlorous (ClO-) has been developed in this paper. Probe NBD-NH2 exhibited excellent sensitivity and high selectivity toward detection of ClO- in CH3CH2OH/HEPES solution (1:4, v/v, 10 mM, pH 7.4), where the detection limit as low as 40 nM. The green fluorescence of NBD-NH2 was distinctly quenched by addition of ClO-. In addition, the new probe was also applied for bioimaging using HeLa cells and exist a critical detection of ClO- in living cells. [GRAPHICS] .

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