文献类型： 外文期刊

作者： Li, Yin-Ting ¹ ; Chen, Bing-Jie ¹ ; Wu, Wei-Du ³ ; Ge, Kun ⁴ ; Wei, Xiao-Yi ⁵ ; Kong, Li-Min ¹ ; Xie, Yuan-Yuan ⁶ ; Gu, J ¹ ;

作者机构： 1.Zhejiang Gongshang Univ, Sch Food Sci & Biotechnol, 18 Xuezheng St, Hangzhou 310018, Zhejiang, Peoples R China

2.Shanghai Acad Agr Sci, 1000 Jinqi Rd, Shanghai 201403, Peoples R China

3.Hangzhou Wahaha Grp Co Ltd, Inst Food Sci, Ave 14, Hangzhou 310018, Zhejiang, Peoples R China

4.Hebei Univ, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Hebei, Peoples R China

5.Shanghai Business Sch, Fac Hospitality Management, Dept Food Sci, Shanghai 200235, Peoples R China

6.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China

7.Zhejiang Univ Technol, Coll Pharm

关键词： Polysaccharide from Satgassum fustforme; Antioxidant activity; Antimicrobial activity

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：6.953； 五年影响因子：6.737 ）

ISSN： 0141-8130

年卷期： 2018 年 118 卷

页码：

收录情况： SCI

摘要： In order to improve the bioactivity of the polysaccharide from Sargassum fusiforme (PSF), the degraded polysaccharide (DPSF) was modified by carboxymethylation, yielding carboxymethylated degraded polysaccharides (CDPSF), which were further modified to generate hydroxamated derivatives (HCDPSF). Both CDPSF and HCDPSF were characterized by Fourier transform infrared spectroscopy. The molecular weight of CDPSF and HCDPSF was found to be 354 kDa and 375 kDa, respectively. The in vitro antioxidant activity of CDPSF and HCDPSF was evaluated by determining the radical scavenging ability and total antioxidant activity. The results indicated that the antioxidant activity of CDPSF and HCDPSF was significantly improved when compared to those of DPSF. Antimicrobial assays indicated that both CDPSF and HCDPSF possessed a marked antimicrobial ability, while DPSF did not exhibit such effects under the same conditions. Such polysaccharide derivatives have potentials in the pharmaceutical and food industries. (C) 2018 Elsevier B.V. All rights reserved.