Replacement of grains with soybean hulls ameliorates SARA-induced impairment of the colonic epithelium barrier function of goats
文献类型： 外文期刊
作者： Zhang, Kai 1 ; Tu, Yuanlu 1 ; Gao, Lipeng 1 ; Meng, Meijuan 1 ; Bai, Yunfeng 1 ;
作者机构： 1.Jiangsu Acad Agr Sci, Circular Agr Res Ctr, Nanjing, Jiangsu, Peoples R China
2.Minist Agr, Key Lab Crop & Livestock Integrated Farming, Nanjing, Jiangsu, Peoples R China
关键词： Goat; SARA; Colonic epithelium; Soybean hulls; Tight junction proteins
期刊名称：BMC VETERINARY RESEARCH （ 影响因子：2.741； 五年影响因子：2.955 ）
ISSN： 1746-6148
年卷期： 2018 年 14 卷
页码：
收录情况： SCI
摘要： BackgroundThe effect of soybean hull feeding on the disruption of colonic epithelium barrier function was investigated in goats fed a high-concentrate diet. Twenty-one Boer goats (live weight, 32.572.26kg; age, 1year) were randomly divided into three groups: low-concentrate diet (LC), high-concentrate diet (HC), and high-concentrate diet with soybean hulls (SH).ResultsWe found that the rumen fluid in the LC and SH group shown a higher pH value compared with the HC group. The mRNA and protein expression levels of extracellular regulated protein kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 mitogen-activated protein kinase (MAPK) in the colonic epithelium were significantly decreased in the SH group than in the HC group. Moreover, in goats fed the HC diet, SH treatment promoted gene expression and protein abundance of claudin-1, claudin-4, occludin, and ZO-1 in the colonic epithelium. Additionally, the injury to the colonic epithelium barrier caused by the HC diet was reversed by SH treatment.Conclusions Our results indicated that supplemental SH feeding reverses the damage to colonic epithelium tight junctions by inhibiting the MAPK signalling pathway and has a protective effect on the colonic epithelium during SARA.
- 相关文献
作者其他论文 更多>>
-
Spatial distribution of clogging substances in drip irrigation emitters fed with reclaimed water
作者：Yao, Yuqian;Shen, Yan;Zhang, Kai;Li, Jingzhi;Xiao, Yang;Li, Yunkai;Yao, Yuqian;Li, Jingzhi;Xiao, Yang;Li, Yunkai;Ma, Changjian
关键词：Emitter clogging; Industrial computed tomography; Spatial distribution; Emitter flow channel
-
Using industrial computed tomography to determine the spatial distribution of clogging substances in drip irrigation emitter flow channels
作者：Yao, Yuqian;Shen, Yan;Zhang, Kai;Li, Jingzhi;Xiao, Yang;Li, Yunkai;Yao, Yuqian;Li, Jingzhi;Xiao, Yang;Li, Yunkai;Ma, Changjian
关键词：agricultural irrigation; clogging substance distribution; emitter clogging; poor-quality water; encrassement de buse individuelle; eau de mauvaise qualit & eacute; irrigation agricole; distribution de substances de l'encrassement
-
Failure behavior of pressure compensating emitter under different operation pressures in drip irrigation systems
作者：Hou, Peng;Hou, Peng;Zhang, Kai;Hou, Shance;Li, Jingzhi;Sun, Zeqiang;Xiao, Yang;Li, Yunkai;Ma, Changjian;Li, Yan;Sun, Zeqiang;Ma, Changjian;Zhang, Kai;Hou, Shance;Li, Jingzhi;Xiao, Yang;Li, Yunkai;Wang, Jia
关键词：Emitter clogging; Flow channel; Diaphragm performance; Relative average discharge; Hydraulic performance
-
Foliar Spraying with Compound Amino Acid-Iron Fertilizer Increases Leaf Fresh Weight, Photosynthesis, and Fe-S Cluster Gene Expression in Peach (Prunus persica (L.) Batsch)
作者：Sheng, Yuting;Cheng, Hao;Wang, Limin;Shen, Jingyuan;Liang, Meixia;Zhang, Kai;Zhang, Hongxia;Song, Zhizhong;Sheng, Yuting;Wang, Limin;Shen, Jingyuan;Liang, Meixia;Zhang, Kai;Zhang, Hongxia;Song, Zhizhong;Cheng, Hao;Wang, Limin;Song, Zhizhong;Tang, Meiling;Kong, Qun;Yu, Mingliang
关键词：
-
Evaluation of Lactobacillus plantarum MTD1 and waste molasses as fermentation modifier to increase silage quality and reduce ruminal greenhouse gas emissions of rice straw
作者：Zhao, Jie;Dong, Zhihao;Li, Junfeng;Chen, Lei;Shao, Tao;Bai, Yunfeng;Jia, Yushan
关键词：Rice straw; Probiotic; Waste molasses; Fermentation quality; Ruminal volatile fatty acids; Greenhouse gases
-
Effects of sugar sources and doses on fermentation dynamics, carbohydrates changes, in vitro digestibility and gas production of rice straw silage
作者：Zhao, Jie;Dong, Zhihao;Li, Junfeng;Chen, Lei;Shao, Tao;Bai, Yunfeng;Jia, Yushan
关键词：Rice straw; sugar sources; fermentation quality; carbohydrates; in vitro digestibility
-
Rumen-derived lipopolysaccharide induced ruminal epithelium barrier damage in goats fed a high-concentrate diet
作者：Zhang, Kai;Meng, Meijuan;Gao, Lipeng;Tu, Yuanlu;Bai, Yunfeng;Zhang, Kai;Meng, Meijuan;Gao, Lipeng;Tu, Yuanlu;Bai, Yunfeng
关键词：Goat; Subacute rumen acidosis; Lipopolysaccharide; Rumen epithelium; Tight junction proteins
