A novel ICT-based two photon and NIR fluorescent probe for labile Fe2+ detection and cell imaging in living cells
文献类型： 外文期刊
作者： Yang, Xiaopeng 1 ; Wang, Yushi 1 ; Liu, Rui 1 ; Zhang, Yongru 1 ; Tang, Jun 1 ; Yang, Er-bing 1 ; Zhang, Di 2 ; Zhao, Yuf 1 ;
作者机构： 1.Zhengzhou Univ, Phosphorus Chem Engn Res Ctr Henan Prov, Coll Chem & Mol Engn, Zhengzhou 450002, Henan, Peoples R China
2.Henan Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Zhengzhou 450002, Henan, Peoples R China
3.Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Peoples R China
关键词： Fluorescent probe; Ferrous ion; Near infrared; Two photon microscopy fluorescence imaging
期刊名称：SENSORS AND ACTUATORS B-CHEMICAL （ 影响因子：7.46； 五年影响因子：6.743 ）
ISSN： 0925-4005
年卷期： 2019 年 288 卷
页码：
收录情况： SCI
摘要： Iron is an essential element for human body, involved in important biochemical processes in the body, especially in biological oxidation. Misregulation of iron levels in the cell is concerned with serious diseases. Here, a novel two photon and turn on NIR-fluorescent probe based ICT for detection of Fe2+ is first reported. The probe exhibited brilliant selectivity and excellent sensitivity (DL = 4.5 mu M), rapid response (15 min) and "naked-eye colorimetric sensor" for monitoring of Fe2+. More importantly, the probe was successfully applied to real-time monitor Fe2+ in living cell through two-photon microscopy fluorescence imaging with excitation 680 nm.
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