文献类型： 外文期刊
作者： Ren, Yi 1 ; Chao, Ling-Hui 1 ; Sun, Jing 1 ; Chen, Xiao-Nan 1 ; Yao, Hui-Na 1 ; Zhu, Zhi-Xiang 1 ; Dong, Dan 2 ; Liu, Tin 1 ;
作者机构： 1.Beijing Univ Chinese Med, Sch Chinese Materia Med, Modern Res Ctr Tradit Chinese Med, Beijing, Peoples R China
2.Beijing Acad Agr & Forestry Sci, Inst Plant & Environm Protect, Beijing, Peoples R China
关键词： Penicillium oxalicum; polyketide; penicilloxalone; anti-neuroinflammatory activity
期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）
ISSN： 1478-6419
年卷期： 2019 年 33 卷 3 期
页码：
收录情况： SCI
摘要： Two new polyketides, penicilloxalones A (1) and B (2), together with 13 known compounds (3-15), were isolated from the ethyl acetate extract of the solid substrate fermentation cultures of the fungus Penicillium oxalicum MHZ153. The structures of the isolates were determined by spectroscopic analysis and comparison of their spectroscopic and physicochemical data with the literature values. Compounds 7 and 11 showed inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC50 values of 0.9 +/- 0.2 mu M and 87.9 +/- 0.7 mu M, respectively. [GRAPHICS] .
- 相关文献
作者其他论文 更多>>
-
Tomato Pectin Ameliorated Hepatic Steatosis in High-Fat-Diet Mice by Modulating Gut Microbiota and Bile Acid Metabolism
作者：Wang, Pan;Sun, Jing;Zhao, Wenting;Wang, Dan;Ma, Yue;Zhao, Yuanyuan;Wang, Yubin;Zhao, Xiaoyan;Sun, Jing;Zhao, Xiaoyan
关键词：tomato pectin; liver steatosis; gut microbiota; bile acids; FXR/FGF15 signaling
-
Polyethylene Glycol Priming Enhances the Seed Germination and Seedling Growth of Scutellaria baicalensis Georgi under Salt Stress
作者：Wang, Renjie;Zeng, Li;Xi, Jiayi;Li, Jun;Li, Chenxuan;Zeng, Li;Liu, Ligong
关键词：Scutellaria baicalensis Georgi; polyethylene glycol (PEG); seed priming; salt tolerance
-
Dietary Tomato Pectin Attenuates Hepatic Insulin Resistance and Inflammation in High-Fat-Diet Mice by Regulating the PI3K/AKT Pathway
作者：Sun, Jing;Wu, Kongyan;Zhang, Chunhong;Sun, Jing;Wu, Kongyan;Wang, Pan;Wang, Yubin;Wang, Dan;Zhao, Wenting;Zhao, Yuanyuan;Zhao, Xiaoyan
关键词：tomato pectin; insulin resistance; PI3K/AKT pathway
-
Antagonistic Activity of Streptomyces alfalfae 11F against Fusarium Wilt of Watermelon and Transcriptome Analysis Provides Insights into the Synthesis of Phenazine-1-Carboxamide
作者：Dong, Dan;Zhang, Taotao;Niu, Zhenfeng;Zhao, Wenyu;Yu, Jiajia;Wu, Huiling;Li, Maoying;Xue, Guoping;Bai, Hongmei;Jiang, Wei
关键词：biological control; Streptomyces alfalfae; differentially expressed genes; secondary metabolites; RNA-seq
-
Fertilization altered co-occurrence patterns and microbial assembly process of ammonia-oxidizing microorganisms
作者：Ma, Mingchao;Zhao, Yubin;Jiang, Xin;Guan, Dawei;Cao, Fengming;Li, Li;Li, Jun;Ma, Mingchao;Zhao, Yubin;Jiang, Xin;Guan, Dawei;Cao, Fengming;Li, Li;Li, Jun;Yuan, Ming;Zhou, Jing;Ding, Jianli
关键词：
-
Comprehensive Profiling of Alternative Splicing and Alternative Polyadenylation during Fruit Ripening in Watermelon (Citrullus lanatus)
作者：Yu, Yongtao;Ren, Yi;Zhang, Jie;Li, Maoying;Tian, Shouwei;Wang, Jinfang;Liao, Shengjin;Gong, Guoyi;Zhang, Haiying;Guo, Shaogui;Liufu, Yuxiang
关键词：watermelon; alternative splicing; alternative polyadenylation; lncRNA; fruit ripening
-
Regionally Compatible Individual Tree Growth Model under the Combined Influence of Environment and Competition
作者：Zhang, Wenjie;Wu, Baoguo;Zhang, Wenjie;Yang, Guijun;Zhang, Wenjie;Yang, Guijun;Wu, Baoguo;Ren, Yi
关键词：regionally compatible; competition; environmental factors; individual tree growth
