Exposure to polystyrene nanoplastics induces apoptosis, autophagy, histopathological damage, and intestinal microbiota dysbiosis of the Pacific whiteleg shrimp (Litopenaeus vannamei)
文献类型： 外文期刊
作者： Li, Yiming 1 ; Yuan, Haojuan 2 ; Rihan, Na 2 ; Liu, Xingguo 1 ; Zhu, Tian 3 ; Zhao, Yunlong 2 ; Che, Xuan 1 ;
作者机构： 1.Chinese Acad Fisheries Sci, Fishery Machinery & Instrument Res Inst, 63 Chifeng Rd, Shanghai 200092, Peoples R China
2.East China Normal Univ, Sch Life Sci, 500 Dongchuan Rd, Shanghai, Peoples R China
3.Univ Sains Malaysia, Ctr Marine & Coastal Studies, Minden 11800, Penang, Malaysia
关键词： Nanoplastics; Litopenaeus vannamei; Immunity; Gut microbiota; Apoptosis
期刊名称：SCIENCE OF THE TOTAL ENVIRONMENT （ 影响因子：9.8； 五年影响因子：9.6 ）
ISSN： 0048-9697
年卷期： 2024 年 919 卷
页码：
收录情况： SCI
摘要： Nanoplastics (NPs) are widely distributed environmental pollutants that can disrupt intestinal immunity of crustaceans. In this study, the effects of NPs on gut immune enzyme activities, cell morphology, apoptosis, and microbiota diversity of Litopenaeus vannamei were investigated. L. vannamei was exposed to five concentrations of NPs (0, 0.1, 1, 5, and 10 mg/L) for 28 days. The results showed that higher concentrations of NPs damaged the intestinal villi, promoted formation of autophagosomes, increased intestinal non-specific immunoenzyme activities, and significantly increased apoptosis at 10 mg/L. In response to exposure to NPs, the expression levels of ATG3, ATG4, ATG12, Caspase-3, p53, and TNF initially increased and then decreased. In addition, the concentration of NPs was negatively correlated to the expression levels of the genes of interest and intestinal enzyme activities, suggesting that exposure to NPs inhibited apoptosis and immune function. The five dominant phyla of the gut microbiota (Proteobacteria, Firmicutes, Bacteroidetes, Acidobacteria, and Actinomycetes) were similar among groups exposed to different concentrations of NPs, but the abundances tended to differ. Notably, exposure to NPs increased the abundance of pathogenic bacteria. These results confirm that exposure to NPs negatively impacted intestinal immune function of L. vannamei. These findings provide useful references for efficient breeding of L. vannamei.
- 相关文献
作者其他论文 更多>>
-
Impacts of Low-Order Stream Connectivity Restoration Projects on Aquatic Habitat and Fish Diversity
作者：Li, Xinfeng;Che, Xuan;Chen, Xiaolong;Tian, Changfeng;Zhang, Jiahua
关键词：river barrier; low-order streams; connectivity restoration projects; aquatic habitat; fish diversity
-
Comparative mechanisms of acute high-alkalinity stress on the normal and hybrid populations of pacific white shrimp (Litopenaeus vannamei)
作者：Ye, Yucong;Liu, Hang;Yuan, Haojuan;Du, Xinglin;Huang, Jiarong;Zhou, Yujie;Zhao, Yunlong;Li, Yiming
关键词：alkaline stress; gene expression; ion transport;
Litopenaeus vannamei ; nitrogen metabolism -
Spatial-temporal dynamics of marine microorganisms in Kuroshio-Oyashio Extension
作者：Zhao, Shanshan;Hu, Xin;Cheng, Yuan;Wang, Yuxuan;Li, Haoshuai;Zhang, Honghai;Li, Yiming;Bao, Mutai;Zhao, Shanshan;Hu, Xin;Cheng, Yuan;Wang, Yuxuan;Li, Haoshuai;Zhang, Honghai;Lu, Jinren;Li, Yiming;Bao, Mutai;Hu, Xin
关键词：Microorganisms; Biodiversity; Community composition; Spatial-temporal dynamic; Kuroshio-Oyashio Extension
-
Classifying watershed based on a semi-supervised approach under limited hydrological data conditions: A case study of the Chishui Watershed, China
作者：Wang, Yue;Xia, Jihong;Cai, Wangwei;Zu, Jiayi;Wang, Qihua;Ji, Shuyi;Ren, Yifei;Huang, Yating;Huang, Siqi;Che, Xuan
关键词：Watershed classification; Physical features; Time-series classification; Semi-supervised Classification; Hydrological process
-
Impact of different culture substrates on the water environment and growth performance of Babylonia areolata in a recirculating aquaculture system
作者：Zhang, Jiahua;Wang, Jie;Gu, Zhaojun;Che, Xuan;Liu, Xingguo;Zhang, Jiahua;Wang, Jie;Gu, Zhaojun;Che, Xuan;Liu, Xingguo
关键词：Babylonia areolata; Recirculating Aquaculture; System Construction; Aquaculture substrate; Growth condition
-
Formation and Characterization of Aerobic Granular Sludge in the Treatment of Tempering Lubricant Wastewater by Hydrolysis Acidification-Aerobic Process
作者：Yang, Guanyi;Lv, Juan;Chen, Chaoyang;Gan, Jiong;Xiao, Fan;Liu, Xingguo
关键词：tempering lubricant wastewater; aerobic granular sludge; hydrolysis acidification-aerobic process; organic loading rate; settling time
-
Ion transport and metabolic regulation induced by nanoplastic toxicity in gill of Litopenaeus vannamei using proteomics
作者：Li, Yiming;Yao, Zongli;Li, Yan;Sun, Zhen;Lai, Qifang;Ye, Yucong;Zhu, Xiaoyi;Rihan, Na;Zhao, Yunlong
关键词：
