Stereoselective study on chiral fungicide metconazole in four kinds of fruits: Absolute configuration, SFC-MS/MS enantioseparation, degradation and risk assessment
文献类型： 外文期刊
作者： Diao, Ziyang 1 ; Di, Shanshan 2 ; Qi, Peipei 2 ; Liu, Zhenzhen 2 ; Wang, Zhiwei 2 ; Zhao, Huiyu 2 ; Wang, Meng 4 ; Zhang, Chenghui 1 ; Wang, Xinquan 2 ;
作者机构： 1.Hainan Univ, Coll Food Sci & Engn, 58 Renmin Ave, Haikou 570228, Hainan, Peoples R China
2.Zhejiang Acad Agr Sci, Inst Agroprod Safety & Nutr, State Key Lab Managing Biot & Chem Threats Qual &, key Lab Detect Pesticide Residues & Control Zhejia, Hangzhou 310021, Peoples R China
3.Agr Minist, Key Lab Pesticide Residue Detect, Hangzhou 310021, Peoples R China
4.Hainan Univ, Key Lab Trop Fruits & Vegetables Qual & Safety Sta, Haikou 570228, Peoples R China
5.Hainan Univ, Coll Plant Protect, Haikou 570228, Peoples R China
关键词： Chiral metconazole; Absolute configuration; SFC-MS/MS enantioseparation; Fruits; Stereoselective degradation
期刊名称：FOOD CHEMISTRY （ 影响因子：8.8； 五年影响因子：8.6 ）
ISSN： 0308-8146
年卷期： 2024 年 438 卷
页码：
收录情况： SCI
摘要： Metconazole is a novel chiral fungicide with two chiral carbon atoms, but the research on its stereoselective behavior is limited. Therefore, the stereoselective behaviors of metconazole in four fruits, including grape, peach, pear and jujube, were summarized in this study. After determining the absolute configuration of metconazole stereoisomers, a chiral separation method through supercritical fluid chromatography/tandem triple quadrupole mass spectrometry was first developed, which combined an improved QuEChERS method obtained the recoveries of 71.6-113 % with RSD <= 19.8 %. The LOD and LOQ were 4.30-95.9 and 10.5-143.2 ng/kg, respectively. Different stereoselective and diastereoselective behaviors were observed in four fruits. Dietary risk assessments of rac-metconazole were performed in populations with different ages and genders. Both acute (RQa, 0.0124-0.140 %) and chronic (HQ, 0.0234-0.0794 %) intake risks were acceptable. The results of this study would contribute to more complete risk assessments of metconazole and provide data for chiral studies.
- 相关文献
作者其他论文 更多>>
-
Insights into the adsorption performance and mechanism of novel 3D bimetallic MOF nanosheets for the high-efficient removal of 6PPD and 6PPD-quinone
作者：Wu, Nannan;Wang, Jiao;Liu, Zhenzhen;Zhao, Huiyu;Di, Shanshan;Wang, Zhiwei;Wang, Xinquan;Qi, Peipei;Zheng, Bing;Zheng, Bing;Di, Shanshan;Wang, Zhiwei;Wang, Xinquan;Qi, Peipei;Di, Shanshan;Wang, Zhiwei;Wang, Xinquan;Qi, Peipei
关键词：3D bimetallic MOFs; 6PPD; 6PPD-quinone; Adsorption mechanism; DFT calculations
-
Current-use pesticides monitoring and ecological risk assessment in vegetable soils at the provincial scale
作者：Zuo, Wei;Zhao, Yang;Qi, Peipei;Zhang, Chunrong;Zhao, Xueping;Wu, Shenggan;An, Xuehua;Liu, Xinju;Cheng, Xi;Tang, Tao;Yu, Yijun
关键词：Soil; Pesticide residue; Spatial distribution; Vegetable type; Ecological risk assessment
-
Development and validation of modified QuEChERS method combined with LC-MS/MS for high-throughput analysis of per- and polyfluoroalkyl substances in fish samples
作者：Liu, Xiaoqi;Shi, Ranran;Liu, Juanjuan;Wang, Xinquan;Liu, Xiaoqi;Liu, Zhenzhen;Zhao, Huiyu;Shi, Ranran;Wang, Jiao;Liu, Juanjuan;Di, Shanshan;Wang, Zhiwei;Wang, Xinquan;Liu, Lianliang;Liu, Lianliang;Qi, Peipei
关键词：PFAS; Integrated QuEChERS; Liquid chromatography -tandem mass; spectrometry; Liquid chromatography-tandem mass; Fe3O4-TiO2
-
Enzymatic and transcriptional level changes induced by the co-presence of lead and procymidone in hook snout carp (Opsariichthys bidens)
作者：Wu, Shenggan;Di, Shanshan;Lv, Lu;Wang, Dou;Wang, Xinquan;Wang, Yanhua
关键词：Combined effect; Aquatic toxicology; Toxic mechanism; Gene expression
-
Review of fruits flavor deterioration in postharvest storage: Odorants, formation mechanism and quality control
作者：Zhao, Huiyu;Zhang, Suling;Ma, Di;Liu, Zhenzhen;Qi, Peipei;Wang, Zhiwei;Di, Shanshan;Wang, Xinquan;Wang, Xinquan
关键词：Fruit; Deterioration odorants; Influencing factors; Formation mechanism
-
Flavor characteristics of key aroma compounds in bayberry juice, fruit, and thinning fruit using HS-SPME coupled with GC/Q-TOF-MS
作者：Zhang, Suling;Wang, Xinquan;Liu, Lianliang;Qi, Peipei;Wang, Zhiwei;Di, Shanshan;Liu, Zhenzhen;Zhang, Suling;Zhao, Huiyu;Tang, Zhiwei;Xia, Qile;Zhang, Suling;Zhao, Huiyu;Tang, Zhiwei;Wang, Xinquan;Liu, Lianliang
关键词：SPME; GC-Q/TOF-MS; Flavor; Bayberry; ROAV
-
Potential effects of individual and combined exposure to tetraconazole and cadmium on zebrafish from the perspective of enantioselectivity and intestinal microbiota
作者：Di, Shanshan;Li, Ying;Song, Beibei;Guo, Chao;Qi, Peipei;Wang, Zhiwei;Liu, Zhenzhen;Zhao, Huiyu;Wang, Xinquan;Di, Shanshan;Li, Ying;Song, Beibei;Guo, Chao;Qi, Peipei;Wang, Zhiwei;Liu, Zhenzhen;Zhao, Huiyu;Wang, Xinquan;Wang, Xinquan
关键词：Tetraconazole enantiomers; Cadmium; Bioaccumulation; Dissipation; Intestinal microbiota
