Estimates of Genomic Heritability and the Marker-Derived Gene for Re(Production) Traits in Xinggao Sheep
文献类型： 外文期刊
作者： Liu, Zaixia 1 ; Fu, Shaoyin 3 ; He, Xiaolong 1 ; Liu, Xuewen 4 ; Shi, Caixia 1 ; Dai, Lingli 1 ; Wang, Biao 3 ; Chai, Yuan 1 ; Liu, Yongbin 6 ; Zhang, Wenguang 1 ;
作者机构： 1.Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot 010018, Peoples R China
2.Inner Mongolia Engn Res Ctr Genom Big Data Agr, Hohhot 010018, Peoples R China
3.Inner Mongolia Acad Agr & Anim Husb Sci, Inst Anim Husb, Hohhot 010031, Peoples R China
4.Xingan Vocat & Tech Coll, Coll Agron Anim Husb & Bioengn, Ulanhot 137400, Peoples R China
5.Inner Mongolia Acad Agr & Anim Husb Sci, Vet Res Inst, Hohhot 010031, Peoples R China
6.Inner Mongolia Univ, Sch Life Sci, Hohhot 010021, Peoples R China
关键词： Xinggao sheep; LS; BWT; WWT; ADG; genetic parameter evaluation; MATs
期刊名称：GENES （ 影响因子：3.5； 五年影响因子：3.9 ）
ISSN：
年卷期： 2023 年 14 卷 3 期
页码：
收录情况： SCI
摘要： Xinggao sheep are a breed of Chinese domestic sheep that are adapted to the extremely cold climatic features of the Hinggan League in China. The economically vital reproductive trait of ewes (litter size, LS) and productive traits of lambs (birth weight, BWT; weaning weight, WWT; and average daily gain, ADG) are expressed in females and later in life after most of the selection decisions have been made. This study estimated the genetic parameters for four traits to explore the genetic mechanisms underlying the variation, and we performed genome-wide association study (GWAS) tests on a small sample size to identify novel marker trait associations (MTAs) associated with prolificacy and growth. We detected two suggestive significant single-nucleotide polymorphisms (SNPs) associated with LS and eight significant SNPs for BWT, WWT, and ADG. These candidate loci and genes also provide valuable information for further fine-mapping of QTLs and improvement of reproductive and productive traits in sheep.
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