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Research Progress of Benzothiazole and Benzoxazole Derivatives in the Discovery of Agricultural Chemicals

文献类型： 外文期刊

作者： Zou, Yue 1 ; Zhang, Yong 1 ; Liu, Xing 1 ; Song, Hongyi 1 ; Cai, Qingfeng 1 ; Wang, Sheng 1 ; Yi, Chongfen 2 ; Chen, Jixiang 1 ;

作者机构： 1.Guizhou Univ, Ctr R&D Fine Chem, Natl Key Lab Green Pesticide, Key Lab Green Pesticide & Agr Bioengn,Minist Educ, Guiyang 550025, Peoples R China

2.Guizhou Acad Agr Sci, Guizhou Rice Res Inst, Guiyang 550025, Peoples R China

关键词： benzoxazole; benzothiazole; agrochemical; SAR; mechanism

期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.6； 五年影响因子：6.2 ）

ISSN： 1661-6596

年卷期： 2023 年 24 卷 13 期

页码：

收录情况： SCI

摘要： Benzoxazole and benzothiazole have a broad spectrum of agricultural biological activities, such as antibacterial, antiviral, and herbicidal activities, which are important fused heterocyclic scaffold structures in agrochemical discovery. In recent years, great progress has been made in the research of benzoxazoles and benzothiazoles, especially in the development of herbicides and insecticides. With the widespread use of benzoxazoles and benzothiazoles, there may be more new products containing benzoxazoles and benzothiazoles in the future. We systematically reviewed the application of benzoxazoles and benzothiazoles in discovering new agrochemicals in the past two decades and summarized the antibacterial, fungicidal, antiviral, herbicidal, and insecticidal activities of the active compounds. We also discussed the structural-activity relationship and mechanism of the active compounds. This work aims to provide inspiration and ideas for the discovery of new agrochemicals based on benzoxazole and benzothiazole.

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