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METABOLOMICS ANALYSIS ON DIFFERENT PARTS OF ACANTHOPANAX SENTICOSUS BASED ON UPLC-Q-TOF-MS

文献类型: 外文期刊

作者: Zuo, Lijie 1 ; Ge, Xinjin 2 ; Cheng, Maogao 1 ; Qiao, Qingmei 1 ; Li, Lihong 1 ; Lv, Huifang 1 ; Xu, Zhikun 1 ; Xu, Shuya 1 ;

作者机构: 1.Henan Univ Anim Husb & Econ, Coll Anim Med, Zhengzhou 450046, Peoples R China

2.Henan Acad Agr Sci, Henan Prov Engn Technol Res Ctr Econ Crop Seedlin, Econ Crop Res Inst, Zhengzhou 450008, Peoples R China

关键词: Acanthopanax senticosus; UPLC-Q-TOF-MS/MS; multivariate statistical analysis; metabolomic

期刊名称:ACTA POLONIAE PHARMACEUTICA ( 2020影响因子:0.33; 五年影响因子:0.667 )

ISSN: 0001-6837

年卷期: 2021 年 78 卷 2 期

页码:

收录情况: SCI

摘要: Acanthopanax senticosus roots, rhizomes, or stems are the main site of ciwujia. Due to the limited resources of the roots, the leaves and pulp are sometimes used as health products or medication sites. In order to utilize the leaves and pulp, it is important to conduct the chemical comparison of the roots, leaves, and pulp of A. senticosus. In this study, Multivariate statistical analysis and UPLC-Q-TOF-MS/MS was used to compare the chemical composition of the roots, leaves, pulp of A. senticosus, a total of 47 compounds were identified. The results suggested that the content of lignans, such as Eleutheroside D, Eleutheroside E, were so much higher in the roots than those in the leaves and pulp. The content of Eleutheroside B is similar between the roots and the pulp of A. senticosus and is so much higher in the roots, pulp than that in the leaves. This result laid a certain foundation for the pulp of A. senticosus to replace the roots as a medication site in some pharmacological effects. The leaves cannot replace the roots as a medication site due to the low content of Eleutheroside compounds. This study laid the foundation for the rational utilization of A. senticosus resources.

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