您好，欢迎访问北京市农林科学院 机构知识库！
北京市农林科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Condensation of STM is critical for shoot meristem maintenance and salt tolerance in Arabidopsis

文献类型： 外文期刊

作者： Cao, Xiuwei 1 ; Du, Qingwei 1 ; Guo, Yahe 5 ; Wang, Ying 3 ; Jiao, Yuling 1 ;

作者机构： 1.Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China

2.Chinese Acad Sci, Inst Genet & Dev Biol, Innovat Acad Seed Design, Natl Ctr Plant Gene Res Beijing, Beijing 100101, Peoples R China

3.Univ Chinese Acad Sci, Coll Life Sci, Beijing 100049, Peoples R China

4.Beijing Acad Agr & Forestry Sci, Beijing Agrobiotechnol Res Ctr, Beijing 100097, Peoples R China

5.Peking Univ, Sch Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China

6.Peking Univ, Acad Adv Interdisciplinary Studies, Peking Tsinghua Ctr Life Sci, Ctr Quantitat Biol, Beijing 100871, Peoples R China

7.Peking Univ, Inst Adv Agr Sci, Shandong Lab Adv Agr Sci Weifang, Weifang 261325, Shandong, Peoples R China

8.Univ Chinese Acad Sci, Coll Adv Agr Sci, Beijing 100049, Peoples R China

关键词： intrinsically disordered proteins; KNOX1; shoot apical meristem; biomolecular condensate; salt stress; axillary meristem

期刊名称：MOLECULAR PLANT （ 影响因子：17.1； 五年影响因子：21.4 ）

ISSN： 1674-2052

年卷期： 2023 年 16 卷 9 期

页码：

收录情况： SCI

摘要： The shoot meristem generates the entire shoot system and is precisely maintained throughout the life cycle under various environmental challenges. In this study, we identified a prion-like domain (PrD) in the key shoot meristem regulator SHOOT MERISTEMLESS (STM), which distinguishes STM from other related KNOX1 proteins. We demonstrated that PrD stimulates STM to form nuclear condensates, which are required for maintaining the shoot meristem. STM nuclear condensate formation is stabilized by selected PrD-containing STM-interacting BELL proteins in vitro and in vivo. Moreover, condensation of STM promotes its interaction with the Mediator complex subunit MED8 and thereby enhances its transcriptional activity. Thus, condensate formation emerges as a novel regulatory mechanism of shoot meristem functions. Furthermore, we found that the formation of STM condensates is enhanced upon salt stress, which allows enhanced salt tolerance and increased shoot branching. Our findings highlight that the transcription factor partitioning plays an important role in cell fate determination and might also act as a tunable environmental acclimation mechanism.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：北京市农林科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台