您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Effects of polystyrene nanoplastics on hormonal regulation and glucose metabolism of Pacific whiteleg shrimp (Litopenaeus vannamei)

文献类型： 外文期刊

作者： Li, Yiming 1 ; Zhu, Bihong 2 ; Zhu, Xiaoyi 2 ; Ye, Yucong 2 ; Liu, Xingguo 1 ; Wang, Xiaodong 1 ; Che, Xuan 1 ; Zhao, Yunlong 2 ;

作者机构： 1.Chinese Acad Fisheries Sci, Fishery Machinery & Instrument Res Inst, 63 Chifeng Rd, Shanghai 200092, Peoples R China

2.East China Normal Univ, Sch Life Sci, 500 Dongchuan Rd, Shanghai 200241, Peoples R China

期刊名称：ENVIRONMENTAL SCIENCE-NANO （ 影响因子：5.8； 五年影响因子：6.7 ）

ISSN： 2051-8153

年卷期： 2024 年

页码：

收录情况： SCI

摘要： Nanoplastics (NPs) as emerging pollutants pose a serious threat due to physiological effects on aquatic organisms, especially crustaceans. Therefore, the aim of the present study was to assess the effects of exposure to NPs on glucose metabolites, hormone content, glucose metabolism-related enzyme activities, and gene expression levels in Litopenaeus vannamei. The results showed that with increasing concentrations of NPs, lactic acid levels were significantly increased in the hemolymph and hepatopancreas, while glucose levels were significantly decreased; serum thyrotropin-releasing hormone levels were significantly increased, while serum levels of glucagon, insulin, and corticotropin-releasing hormones were significantly decreased; the activities of the glucose metabolism-related enzymes phosphofructokinase (PFK), phosphoenolpyruvate carboxykinase (PEPCK), and hepatopancreatic hexokinase (HK) initially increased and then decreased, while the activity of pyruvate kinase (PK) gradually decreased; the expression levels of HK, PFK, PK, fructose-1,6-bisphosphatase, glucose 6-phosphatase, and PEPCK first increased and then decreased, while the expression levels of glucose transporter 2 and glycogen synthase kinase-3 beta were significantly decreased. The results of metabolomics analysis showed that NPs may affect glucose metabolites via inhibition of the pentose phosphate pathway. These results suggest that NPs can interfere with glucose metabolism of L. vannamei by affecting glucose metabolites, hormone levels, enzyme activities, and gene expression levels. The results of this study offer valuable insights into the effects of exposure to NPs on the glucose metabolism of crustaceans.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台