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AN HYPOTHESIS ON CRUSTACEAN PIGMENTATION METABOLISM: L-CARNITINE AND NUCLEAR HORMONE RECEPTORS AS LIMITING FACTORS

文献类型: 外文期刊

作者: Ghonimy, Abdallah 1 ; Greco, Laura S. Lopez 4 ; Li, Jian 1 ; Wade, Nicholas M. 5 ;

作者机构: 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Natl Key Lab Mariculture Biobreeding & Sustainable, Qingdao 266071, Peoples R China

2.Qingdao Natl Lab Marine Sci & Technol, Funct Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266071, Peoples R China

3.Suez Canal Univ, Fish Farming & Technol Inst, Ismailia 41522, Egypt

4.Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Biodivers & Decapodos, Inst Biodivers & Biol Expt & Aplicada IBBEA,CONICE, 1428EGA, Buenos Aires, Argentina

5.Univ Edinburgh, Roslin Inst, Edinburgh EH25 9RG, Scotland

6.Univ Edinburgh, Royal Dick Sch Vet Studies, Edinburgh EH25 9RG, Scotland

关键词: Astaxanthin; astaxanthin ester; carnitine; crustacyanin; long chain fatty acid; PPAR

期刊名称:CRUSTACEANA ( 影响因子:0.6; 五年影响因子:0.5 )

ISSN: 0011-216X

年卷期: 2023 年 96 卷 10 期

页码:

收录情况: SCI

摘要: Astaxanthin (Axn) is the primary pigment molecule in crustaceans associated with quality, health and growth traits, leading to increased marketing value. Axn can be contained within the protein complex crustacyanin (CRCN) to produce an array of different shell colours, or esterified with fatty acids (FA) for storage but also contributing additional red colouration. L-Carnitine (LC) has a major role in FA oxidation and mitochondrial function optimization, which could influence the proportion of Axn complexed with FA or CRCN. Peroxisome proliferator activated receptors (PPARs) have important roles in FA and Axn uptake, and stored lipid oxidation affecting Axn homeostasis and storage in lipid bodies. Whether Axn could increase PPAR signalling and carnitine palmitoyl transferase activity, leading to induction of lipid metabolism, is not known in crustaceans. Several FA have been shown to preferentially form FA Axn-esters, including saturated fatty acids (SFA) such as C16:0 and C18:0, mono-unsaturated fatty acids (MUFA) such as C16:1 and C18:1, and poly-unsaturated fatty acids (PUFA) such as C20:4, C20:5, and C20:6. We hypothesize that manipulating the dietary ratios and inclusion of LC, Axn, and specific FA may be able to further improve pigment utilization, lipid metabolism, health, and growth in crustaceans.

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