Ternary Mixture of Azoxystrobin, Boscalid and Pyraclostrobin Disrupts the Gut Microbiota and Metabolic Balance of Honeybees (Apis cerana cerana)
文献类型： 外文期刊
作者： Dong, Jie 1 ; Huang, Minjie 1 ; Guo, Haikun 2 ; Zhang, Jiawen 1 ; Tan, Xiaodong 1 ; Wang, Deqian 1 ;
作者机构： 1.Zhejiang Acad Agr Sci, Inst Anim Husb & Vet Sci, Hangzhou 310021, Peoples R China
2.Zhejiang Acad Agr Sci, Inst Agroprod Safety & Nutr, Hangzhou 310021, Peoples R China
关键词： azoxystrobin; boscalid; pyraclostrobin; metabolome; gut microbiota; Apis cerana
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.6； 五年影响因子：6.2 ）
ISSN：
年卷期： 2023 年 24 卷 6 期
页码：
收录情况： SCI
摘要： There is a growing risk of pollinators being exposed to multiple fungicides due to the widespread use of fungicides for plant protection. A safety assessment of honeybees exposed to multiple commonly used fungicides is urgently required. Therefore, the acute oral toxicity of the ternary mixed fungicide of ABP (azoxystrobin: boscalid: pyraclostrobin = 1:1:1, m/m/m) was tested on honeybees (Apis cerana cerana), and its sublethal effect on foragers' guts was evaluated. The results showed that the acute oral median lethal concentration (LD50) of ABP for foragers was 12.6 mu g a.i./bee. ABP caused disorder of the morphological structure of midgut tissue and affected the intestinal metabolism; the composition and structure of the intestinal microbial community was perturbed, which altered its function. Moreover, the transcripts of genes involved in detoxification and immunity were strongly upregulated with ABP treatment. The study implies that exposure to a fungicide mixture of ABP can cause a series of negative effects on the health of foragers. This work provides a comprehensive understanding of the comprehensive effects of common fungicides on non-target pollinators in the context of ecological risk assessment and the future use of fungicides in agriculture.
- 相关文献
作者其他论文 更多>>
-
Novel Insights into the Circadian Rhythms Based on Long Noncoding and Circular RNA Profiling
作者：Tan, Xiaodong;Zhang, Jiawen;Dong, Jie;Huang, Minjie;Zhou, Zhenzhen;Wang, Deqian
关键词：circadian rhythm; long noncoding RNA; circular RNA; hypothalamus; AOX1
-
Whole-genome variants dataset of 209 local chickens from China
作者：Tan, Xiaodong;Zhang, Jiawen;Dong, Jie;Huang, Minjie;Zhou, Zhenzhen;Yang, Shuyuan;Wang, Deqian;Li, Qinghai;Wang, Huanhuan;Bai, Lijuan;Cui, Ming
关键词：
-
Uncovering hidden dangers: The combined toxicity of abamectin and lambda-cyhalothrin on honey bees
作者：Chen, Xiaozhen;Chen, Xiaozhen;Wang, Feidi;Guo, Haikun;Liu, Xinju;Wu, Shenggan;Lv, Lu;Tang, Tao;Lv, Lu;Tang, Tao
关键词：Honey bees; Insecticides; Combined toxicity; Gut microbiota; Immune system; Detoxification
-
Genome-wide detections for runs of homozygosity and selective signatures reveal novel candidate genes under domestication in chickens
作者：Tan, Xiaodong;Dong, Jie;Huang, Minjie;Zhang, Jiawen;Zhou, Zhenzhen;Wang, Deqian;Liu, Lu;Li, Weifen;Liu, Lu;Xiang, Yun;Li, Qinghai;Wang, Huanhuan;Bai, Lijuan;Cui, Ming;Wu, De
关键词：Indigenous chickens; Genomic inbreeding; Runs of homozygosity; Selective signature; Transcriptome; VSTM2A
-
Ecotoxicological effects of common fungicides on the eastern honeybee Apis cerana cerana (Hymenoptera)
作者：Huang, Minjie;Dong, Jie;Yang, Shuyuan;Xiao, Minghui;Zhang, Jiawen;Wang, Deqian;Yang, Shuyuan;Xiao, Minghui;Guo, Haikun
关键词：Apis cerana; Fungicide exposure; Gut; Risk assessment; Sublethal effects
-
A postmeiotically bifurcated roadmap of honeybee spermatogenesis marked by phylogenetically restricted genes
作者：Yin, Zhiyong;Xue, Yingdi;Yu, Xianghui;Ma, Jun;He, Feng;Ding, Guiling;Huang, Jiaxing;Ding, Guiling;Huang, Jiaxing;Dong, Jie;Ma, Jun;He, Feng;Ma, Jun;He, Feng;Ma, Jun;He, Feng
关键词：
-
The joint effects of ultrasound and modified atmosphere packaging on the storage of sauced ducks
作者：Mao, Tingting;Xia, Chenlan;Xia, Qiang;Zhou, Changyu;Cao, Jinxuan;He, Jun;Pan, Daodong;Zeng, Tao;Wang, Deqian;He, Jun
关键词：Sauced duck; Ultrasound; Modified atmosphere packaging; Microbial diversity; Shelf life
