文献类型: 外文期刊
作者: Zhang, Jing 2 ; Liu, Ying-Qian 1 ; Yang, Liu 3 ; Feng, Gang 2 ;
作者机构: 1.Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China
2.Chinese Acad Trop Agr Sci, Environm & Plant Protect Inst, Danzhou 571737, Peoples R China
3.Lanzhou Jiaotong Univ, Environm & Municipal Engn Sch, Lanzhou 730000, Peoples R China
关键词: Brontispa longissima;Insecticidal activity;Podophyllotoxin;Structure-activity relationships
期刊名称:NATURAL PRODUCT COMMUNICATIONS ( 影响因子:0.986; 五年影响因子:1.068 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: In an attempt to find biorational insecticides, eleven podophyllotoxin analogues were tested for their insecticidal activity against the fifth-instar larvae of Brontispa longissima in vivo for the first time. Among all of the tested compounds, deoxypodophyllotoxin (3) and β-apopicropodophyllin (4) showed more promising and pronounced insecticidal activity than toosendanin, a commercial insecticide derived from Melia toosendan, and important SAR information has been revealed. Together, these preliminary results may be useful in guiding further modification of podophyllotoxins in the development of potential new insecticides.
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