文献类型： 外文期刊

作者： Wu, Hai-Yan ¹ ; Dong, Chen-Fan ¹ ; Zheng, Guan-Chao ¹ ; Zhang, Zhi-Hua ³ ; Zhang, Ya-Ya ¹ ; Tan, Zhi-Jun ¹ ; Gu, Hai-Feng ⁵ ;

作者机构： 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Minist Agr & Rural Affairs, Key Lab Testing & Evaluat Aquat Prod Safety & Qua, Qingdao 266071, Peoples R China

2.Shanghai Ocean Univ, Coll Food Sci & Technol, Shanghai 201306, Peoples R China

3.Hebei Prov Aquat Prod Qual Inspect & Testing Stn, Shijiazhuang 050011, Peoples R China

4.Pilot Natl Lab Marine Sci & Technol Qingdao, Qingdao 266071, Peoples R China

5.Minist Nat Resources, Inst Oceanog 3, Xiamen 361005, Peoples R China

关键词： Alexandrium catenella; Mussel; Paralytic shellfish toxin; Biotransformation

期刊名称：ENVIRONMENTAL POLLUTION （ 影响因子：9.988； 五年影响因子：10.366 ）

ISSN： 0269-7491

年卷期： 2022 年 313 卷

页码：

收录情况： SCI

摘要： In the last 5 years, paralytic shellfish toxins (PSTs) have been recurrently detected in mollusks farmed in the mussel culture area of Qinhuangdao city, along with the occurrence of toxic outbreaks linked to dinoflagellate species of the Alexandrium genus. To understand the formation mechanism and variation of these events, continuous and comprehensive PSTs monitoring was carried out between 2017 and 2020. Through the analysis of both phytoplankton and cysts via light microscopy and quantitative polymerase chain reaction, it was shown that Alexandrium catenella was responsible for the production of PSTs, which consisted mainly of gonyautoxins 1,4 (GTX1/4, 87%) and GTX2/3 (13%). During bloom events in 2019, mussels accumulated the highest PSTs value (929 mu g STX di-HCl eq center dot kg 1) in conjunction with the peak of cell abundances, and toxin profiles were consistent with high distributions of GTX1/4, GTX2/3, and Neosaxitoxin. Toxin metabolites vary in different substances and mainly transferred to a stable proportion of a-epimer: ss-epimers 3:1. The environmental drivers of Alexandrium blooms included the continuous rise of water temperature (>4.C) and calm weather with low wind speed and no significant precipitation. By comparing toxin profiles and method sensitivity, it was found that dissolved toxins in seawater are more useful for early warning. These results have important implications for the effective monitoring and management of paralytic shellfish poisoning outbreaks.