您好,欢迎访问广东省农业科学院 机构知识库!

Effects of Simulated In Vitro Digestion on the Structural Characteristics, Inhibitory Activity on alpha-Glucosidase, and Fermentation Behaviours of a Polysaccharide from Anemarrhena asphodeloides Bunge

文献类型: 外文期刊

作者: Chen, Juncheng 1 ; Lan, Meijuan 2 ; Zhang, Xia 2 ; Jiao, Wenjuan 3 ; Chen, Zhiyi 3 ; Li, Lin 4 ; Li, Bing 2 ;

作者机构: 1.Hainan Med Univ, Int Sch Publ Hlth & 1 Hlth, Haikou 571199, Peoples R China

2.South China Univ Technol, Engn Res Ctr Starch & Plant Prot Deep Proc, Guangdong Prov Key Lab Green Proc Nat Prod & Prod, Sch Food Sci & Engn,Minist Educ, Guangzhou 510640, Peoples R China

3.Minist Agr & Rural Affairs, Sericultural & Agrifood Res Inst, Guangdong Acad Agr Sci Key Lab Funct Foods, Guangdong Key Lab Agr Prod Proc, Guangzhou 510610, Peoples R China

4.Quanzhou Normal Univ, Coll Oceanol & Food Sci, Food Chem & Technol, Quanzhou 362000, Peoples R China

关键词: polysaccharide; Anemarrhena asphodeloides Bunge; salivary-gastrointestinal digestion; gut microbiota

期刊名称:NUTRIENTS ( 影响因子:5.9; 五年影响因子:6.6 )

ISSN:

年卷期: 2023 年 15 卷 8 期

页码:

收录情况: SCI

摘要: The purpose of this study is to investigate the effects of the simulated saliva-gastrointestinal digestion of AABP-2B on its structural features, inhibitory alpha-glucosidase activity, and human gut microbiota. The salivary-gastrointestinal digestion results show that there is no significant change in the molecular weight of AABP-2B, and no free monosaccharides are released. This indicates that, under a simulated digestive condition, AABP-2B is not degraded and can be further utilized by gut microbiota. AABP-2B still possessed good inhibitory activity on alpha-glucosidase after salivary-gastrointestinal digestion, which may be attributed to the largely unchanged structural characteristics of AABP-2B after simulated digestion. Furthermore, in vitro fecal fermentation with AABP-2B after salivary-gastrointestinal digestion showed that AABP-2B modulated the gut microbiota structure and increased the relative proportions of Prevotella, Faecalibacterium, and Megasphaera. AABP-2B can also modify the intestinal flora composition by inhibiting pathogen growth. Moreover, the AABP-2B group resulted in a significant increase in short-chain fatty acid (SCFAs) content during fermentation. These findings demonstrate that AABP-2B can be used as a prebiotic or functional food to promote gut health.

  • 相关文献
作者其他论文 更多>>