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Encapsulation of Imazalil in HKUST-1 with Versatile Antimicrobial Activity

文献类型: 外文期刊

作者: Dong, Hongqiang 2 ; He, Yuke 3 ; Fan, Chen 4 ; Zhu, Zhongqiang 2 ; Zhang, Chunrong 1 ; Liu, Xinju 1 ; Qian, Kun 3 ; Tang, Tao 1 ;

作者机构: 1.Zhejiang Acad Agr Sci, Inst Agroprod Safety & Nutr, Minist Agr & Rural Affairs, Key Lab Pesticide Residue Detect,State Key Lab Ma, Hangzhou 310021, Peoples R China

2.Tarim Univ, Coll Agr, Alaer 843300, Peoples R China

3.Southwest Univ, Coll Plant Protect, Chongqing 400716, Peoples R China

4.Beijing Technol & Business Univ, Beijing Higher Inst Engn Res Ctr Food Addit & Ing, Beijing 100048, Peoples R China

关键词: imazalil; ionic liquid; HKUST-1; antimicrobial activity; safety

期刊名称:NANOMATERIALS ( 影响因子:5.719; 五年影响因子:5.81 )

ISSN:

年卷期: 2022 年 12 卷 21 期

页码:

收录情况: SCI

摘要: Based on high surface areas, adjustable porosity and microbicide activity, metal-organic frameworks (MOFs) HKUST-1 are widely used as drug release carriers for their slow degradation characteristics under slightly acidic conditions. In this work, porous HKUST-1 was reacted rapidly by cholinium salt (as the deprotonation agent and template) in an aqueous solution at room temperature. A novel antimicrobial system based on an imazalil encapsulated metal organic framework (imazalil IL-3@HKUST-1) was established. Imazalil IL-3@HKUST-1 could achieve synergism in inhibiting pathogenic fungi and bacteria. Moreover, six days after treatment, the slow and constant release of imazalil from imazalil IL@HKUST-1 exhibited better sustainability and microbicidal activity than imazalil. We believe that the method may provide a new strategy for related plant diseases caused by bacteria or fungi.

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