您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Novel Catabolic Pathway of Quercetin-3-O-Rutinose-7-O-alpha-L-Rhamnoside by Lactobacillus plantarum GDMCC 1.140: The Direct Fission of C-Ring

文献类型： 外文期刊

作者： Huang, Guitao 1 ; Lai, Mingwen 1 ; Xu, Canhua 1 ; He, Shan 1 ; Dong, Lihong 2 ; Huang, Fei 2 ; Zhang, Ruifen 2 ; Young, David James 3 ; Liu, Hesheng 4 ; Su, Dongxiao 1 ;

作者机构： 1.Guangzhou Univ, Sch Chem & Chem Engn, Guangzhou, Peoples R China

2.Guangdong Acad Agr Sci, Sericultural & Agri Food Res Inst, Minist Agr & Rural Affairs, Key Lab Funct Foods,Guangdong Key Lab Agr Prod Pr, Guangzhou, Peoples R China

3.Charles Darwin Univ, Coll Engn Informat Technol & Environm, Darwin, NT, Australia

4.Zhejiang Wanli Univ, Zhejiang Prov Top Discipline Biol Engn Level A, Ningbo, Zhejiang, Peoples R China

关键词： Bacteroides uniformis; Lactobacillus; lychee; gut microbiota; C-ring fission

期刊名称：FRONTIERS IN NUTRITION （ 影响因子：6.59； 五年影响因子：6.873 ）

ISSN： 2296-861X

年卷期： 2022 年 9 卷

页码：

收录情况： SCI

摘要： Lychee pulp phenolics (LPP) is mainly catabolized in the host colon, increasing the abundances of Bacteroides and Lactobacillus. Herein, five selected gut microbial strains (Bacteroides uniformis, B. thetaiotaomicron, Lactobacillus rhamnosus, L. plantarum, and L. acidophilus) were separately incubated with LPP to ascertain the specific strains participating in phenolic metabolism and the corresponding metabolites. The results indicated that B. uniformis, L. rhamnosus, and L. plantarum were involved in LPP utilization, contributing to 52.37, 28.33, and 45.11% of LPP degradation after 48 h fermentation, respectively. Unprecedentedly, the metabolic pathway of the major phenolic compound quercetin-3-O-rutinose-7-O-alpha-L-rhamnoside by L. plantarum, appeared to be the direct fission of C-ring at C2-O1 and C3-C4 bonds, which was proved from the occurrence of two substances with the deprotonated molecule [M-H](-) ion at m/z 299 and 459, respectively. Meanwhile, it was fully confirmed that B. uniformis participated in the catabolism of isorhamnetin glycoside and procyanidin B2. In the B. uniformis culture, kaempferol was synthesized through dehydroxylation of quercetin which could be catabolized into alphitonin by L. rhamnosus. Furthermore, LPP metabolites exerted higher antioxidant activity than their precursors and gave clues to understand the interindividual differences for phenolic metabolism by gut microbiota.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台