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Identification of Latent Periodicity in Domains of Alkaline Proteases

文献类型: 外文期刊

作者: Ji, Xiaofeng 1 ; Sheng, Jun 1 ; Wang, Fang 1 ; Zhang, Suzhen 2 ; Hao, Jianhua 1 ; Wang, Haiying 1 ; Sun, Mi 1 ;

作者机构: 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Shandong, Peoples R China

2.Dezhou Univ, Dept Phys, Dezhou 253023, Shandong, Peoples R China

关键词: latent periodicity;alkaline protease;correlation;primary sequence

期刊名称:BIOCHEMISTRY-MOSCOW ( 影响因子:2.487; 五年影响因子:2.57 )

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收录情况: SCI

摘要: Internal repeats in protein sequences have wide-ranging implications for the structure and function of proteins. A keen analysis of the repeats in protein sequences may help us to better understand the structural organization of proteins and their evolutionary relations. In this paper, a mathematical method for searching for latent periodicity in protein sequences is developed. Using this method, we identified simple sequence repeats in the alkaline proteases and found that the sequences could show the same periodicity as their tertiary structures. This result may help us to reduce difficulties in the study of the relationship between sequences and their structures.

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