Molecular characterization of CART, AgRP, and MC4R genes and their expression with fasting and re-feeding in common carp (Cyprinus carpio)
文献类型: 外文期刊
作者: Wan, Yumei 1 ; Zhang, Yan 1 ; Ji, Peifeng 1 ; Li, Yan 1 ; Xu, Peng 1 ; Sun, Xiaowen 1 ;
作者机构: 1.Chinese Acad Fishery Sci, Ctr Appl Aquat Genom, Beijing 100141, Peoples R China
2.Dalian Ocean Univ, Coll Life Sci & Technol, Dalian 116023, Peoples R China
3.Shanghai Ocean Univ, Coll Fisheries & Life Sci, Shanghai 201306, Peoples R China
4.Chinese Acad Fishery Sci, Heilongjiang Fisheries Res Inst, Harbin 150070, Peoples R China
关键词: Common carp;CART;AgRP;MC4R;Teleost;Gene expression
期刊名称:MOLECULAR BIOLOGY REPORTS ( 影响因子:2.316; 五年影响因子:2.357 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: Cocaine and amphetamine-regulated transcript (CART), agouti-related proteins (AgRP) and Melanocortin 4 Receptor (MC4R) involves in the control of appetite. The genes were cloned and characterized, and their regulation was studied in common carp. The CARTI and CARTII genes encode 117- and 120-amino acids, respectively. The AgRP-1 and AgRP-2 genes encode 128- and 136-amino acids, respectively. CARTI was principally expressed in the brain, eye and ovary, while CARTII was highly expressed in the brain. AgRP-1 was strongly expressed in the brain, intestine, testis and eye, while AgRP-2 was highly expressed only in the gill and eye. The MC4R gene, encoding 326-amino acids, was mainly expressed in the brain testis, pituitary and eye. Phylogenetic analysis had been conducted which implied that both CARTI/CARTII and AgRP-1/AgRP-2 might derived from gene duplication events during genome evolution of common carp. CART, AgRP and MC4R gene expression in brain were decreased after fasting treatment and increased sharply after refeeding comparing with normal fed controls, which suggested that CART, AgRP and MC4R are involved in appetite regulation in common carp.
- 相关文献
作者其他论文 更多>>
-
Integrative analysis of miRNA-mRNA expression in the brain during high temperature-induced masculinization of female Nile tilapia ( Oreochromis niloticus )
作者:Jiang, Bingjie;Lu, Siqi;Dong, Yalun;Xu, Pao;Qiang, Jun;Tao, Yifan;Li, Yan;Xu, Pao;Qiang, Jun;Badran, M. F.;Qiang, Jun;Tao, Yifan
关键词:Oreochromis niloticus; Brain tissues; High temperature -induced; Sex reversal; miRNA-mRNA expression
-
Changes in size-dependent Chlorophyll a concentration and group-specific picophytoplankton abundance in short-term nutrient-addition experiments in the Equatorial Eastern Indian Ocean
作者:Sun, Ping;Xu, Zongjun;Li, Yan;Zhang, Xuelei;Wang, Zongling;Sun, Ping;Zhou, Yuping;Sun, Kai-Ming;Liu, Lu;Yuan, Chao
关键词:phytoplankton; chlorophyll a; size-dependent responses; incubation; nutrient; short-term disturbance; Indian ocean
-
Effects of saline and alkaline stresses on the survival, growth, and physiological responses in juvenile mandarin fish ( Siniperca chuatsi )
作者:Li, Yan;Gao, Pengcheng;Zhou, Kai;Yao, Zongli;Sun, Zhen;Qin, Hecai;Lai, Qifang;Li, Yan;Gao, Pengcheng;Zhou, Kai;Yao, Zongli;Sun, Zhen;Qin, Hecai;Lai, Qifang
关键词:Salinity; Alkalinity; Siniperca chuatsi; Growth performance; Physiological regulation
-
Effects of phosphorus on growth, biochemical parameters and intestinal microbiota of the juvenile hybrid of Acipenser baerii 9xAcipenser schrenckii ♂
作者:Chu, Zhipeng;Jin, Jiali;Li, Luoxin;Liu, Wei;Ruan, Rui;Li, Chuangju;Zhou, Wenbo;Chai, Yi;Chu, Zhipeng;Li, Luoxin;Hong, Yucong;Chai, Yi;Chu, Zhipeng;Li, Yan;Sun, Jianwei
关键词:Hybrid sturgeon; Phosphorus; Growth; Serum biochemical; Intestinal microbiota
-
Flow Field Characteristics of Multi-Trophic Artificial Reef Based on Computation Fluid Dynamics
作者:Huang, Junlin;Li, Yan;Xia, Xu;Li, Jiao;Gong, Pihai;Guan, Changtao;Li, Jiao;Gong, Pihai;Guan, Changtao
关键词:artificial reef; flow field characteristics; computation fluid dynamics; multi-trophic structure
-
Comparative transcriptomics and metabolomics reveal specific biochemical responses in cultured largemouth bass ( Micropterus salmoides ) juveniles with sexual dimorphism
作者:Li, Yan;Wang, Qingchun;Qiang, Jun;Xu, Pao;Li, Yan;Hua, Jixiang;Tao, Yifan;Lu, Siqi;Dong, Yalun;Jiang, Bingjie;Qiang, Jun;Xu, Pao
关键词:Largemouth bass; Sexual dependence; Lipid droplets; Differentially expressed genes; Differential metabolites
-
Proline metabolism and its osmotic regulatory role in enhancing hypersalinity tolerance of the razor clam (Sinonovacula constricta)
作者:Li, Yan;Li, Yifeng;Lai, Qifang;Yao, Zongli;Zhou, Kai;Niu, Donghong;Li, Yan;Lai, Qifang;Yao, Zongli;Zhou, Kai;Li, Yifeng;Niu, Donghong;Niu, Donghong
关键词:Sinonovacula constricta; Hypersalinity stress; Proline; Heterologously expressed; Osmoregulation