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Aptamers as Recognition Elements for Analysis of Small Molecules

文献类型: 外文期刊

作者: Zhang, Qiang 1 ; Liu, Xianjin 1 ; Liu, Yuan 1 ;

作者机构: 1.Jiangsu Acad Agr Sci, Key Lab Food Safety Monitoring & Management, Minist Agr, Nanjing, Jiangsu, Peoples R China

2.Jiamusi Univ, Sch Publ Hlth, Jiamusi, Peoples R China

关键词: Aptamer;Small molecules;Biosensor;Analysis.

期刊名称:ASIAN JOURNAL OF CHEMISTRY ( 影响因子:0.355; 五年影响因子:0.293 )

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收录情况: SCI

摘要: Aptamers, which are functional oligonucleotides selected from random-sequence nucleic acids libraries in vitro, possess high recognition ability to specific targets. Owing to their inherent selectivity, affinity and multifarious advantages over the traditional recognition elements, aptamers can be considered as a valid alternative to antibodies or other biomimetic receptors and have been widely employed to design novel analytical methods. In this review, the evolving use of aptamers in analysis of small molecules by exploiting their molecular recognition properties is discussed.

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[2]Aptamer-Based Fluorescence Assay for Hg2+ Determination. Lei Zhao-Jing,Hu Qiu-Hui,Lei Zhao-Jing,Zhang Cun-Zheng,Liu Yuan,Zhang Qiang,Liu Xian-Jin. 2012

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