文献类型： 外文期刊
作者： The Luong Nguyen 1 ; Chen, Jin; Hu, Yuanliang 1 ; Wang, Deyun 1 ; Fan, Yunpeng 1 ; Wang, Junmin 1 ; Abula, Saifudin 1 ;
作者机构： 1.Nanjing Agr Univ, Coll Vet Med, Inst Tradit Chinese Vet Med, Nanjing 210095, Jiangsu, Peoples R China
2.Nanjing Agr Univ, Coll Vet Med, Inst Tradit Chinese Vet Med, Nanjing 210095, Jiangsu, Peoples R C
关键词： Sulfated Auricularia auricula polysaccharide;Newcastle disease virus;Cellular infectivity
期刊名称：CARBOHYDRATE POLYMERS （ 影响因子：9.381； 五年影响因子：8.678 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Total Auricularia auricula polysaccharide (AAP_t) was prepared by extracting and removing the proteins. Column chromatography was used to further graded it into AAP1 and AAP2. Three AAPs were modified by chlorosulfonic acid-pyridine method to obtain three sulfated AAPs (sAAPs), sAAP_t, sAAP1 and SAAP2, respectively. Three sAAPs and Newcastle disease virus (NDV) were added into cultivation system of chicken embryo fibroblast (CEF) in three manners, pre-, post- and simultaneous-adding polysaccharide with NDV respectively, taking three non-modified AAPs as control. Their anti-viral activities were compared by MTT method. The results showed that sAAPs and AAPs at a certain concentration could significantly inhibit the cellular infectivity of NDV in three manners. The effects of sAAPs were better than that of AAPs. It indicated that sulfated modification could enhance the antiviral activity of AAP. sAAP1 and sAAP_t possessed stronger activity and would be as the component of a new-type antiviral drug.
- 相关文献
作者其他论文 更多>>
-
Pickering emulsions constructed on the basis of nanostructured lipid carriers: Effect of carrier models and volume fractions
作者：Liu, Dian;Feng, Jin;Nasiru, Mustapha Muhammad;Zhang, Jing;Li, Chunyang;Nasiru, Mustapha Muhammad;Zhu, Hequan;Xu, Cunfa;Li, Chunyang
关键词：Nanostructured lipid carriers; Pickering emulsions; Inversion; Stability; Simulated digestion
-
The bacterial community drive the humification and greenhouse gas emissions during plant residues composting under different aeration rates
作者：Gu, Junyu;Cao, Yun;Sun, Qian;Zhang, Jing;Xu, Yueding;Jin, Hongmei;Huang, Hongying;Gu, Junyu;Cao, Yun;Jin, Hongmei;Cao, Yun;Sun, Qian;Jin, Hongmei;Cao, Yun;Sun, Qian;Zhang, Jing;Xu, Yueding;Jin, Hongmei;Huang, Hongying
关键词：Spent mushroom substrate; lignocellulosic plant residues; composting; humic acid; microbial community
-
Under what circumstances can chemical oxidation processes effectively degrade antibiotics resistance genes? Evidence from meta-analysis
作者：Ren, Zhuo;Ma, Xijun;Zhang, Jing;Ren, Zhuo;Yang, Bei;Hou, Pengfu;He, Shiying;Xue, Lihong;Yang, Linzhang;Petropoulos, Evangelos;Petropoulos, Evangelos;Liu, Hao
关键词：Chemical oxidation processes; Degradation; Antibiotics resistance genes; Meta -analysis
-
Analysis of CVC1302-Mediated Enhancement of Monocyte Recruitment in Inducing Immune Responses
作者：Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan;Yu, Xiaoming;Hou, Liting;Zhang, Yuanpeng;Li, Lan;Qiao, Xuwen;Cheng, Haiwei;Du, Luping;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Lu, Haiyan
关键词：CVC1302; monocyte; CXCL9; CXCL10; antigen
-
Mushroom alcohol(1-octen-3-ol)and other 7 aroma compounds selected from Chinese dry-cured hams can enhance saltiness perception
作者：Xiao, Zuobing;Liu, Longxue;Niu, Yunwei;Zhang, Jing;Xiao, Zuobing;Wang, Daoying;Zhou, Cunshan
关键词：Odor-induced saltiness enhancement; Chinese dry-cured hams; Key volatile compounds; Different concentration NaCl solution
-
Conventional dendritic cells 2, the targeted antigen-presenting-cell, induces enhanced type 1 immune responses in mice immunized with CVC1302 in oil formulation
作者：Du, Luping;Lu, Haiyan;Qiao, Xuwen;Zhang, Yuanpeng;Hou, Liting;Yu, Xiaoming;Cheng, Haiwei;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Du, Luping;Lu, Haiyan;Qiao, Xuwen;Zhang, Yuanpeng;Hou, Liting;Yu, Xiaoming;Cheng, Haiwei;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Du, Luping;Lu, Haiyan;Qiao, Xuwen;Zhang, Yuanpeng;Hou, Liting;Yu, Xiaoming;Cheng, Haiwei;Chen, Jin;Zheng, Qisheng;Hou, Jibo;Tong, Guangzhi;Lu, Haiyan;Chen, Jin;Zheng, Qisheng
关键词：CVC1302; Oil formulation; Interfollicular region; Inflammatory niche; Th1 cells
-
Cistanche deserticola polysaccharide- functionalized dendritic fibrous nano-silica- based adjuvant for H 9 N 2 oral vaccine enhance systemic and mucosal immunity in chickens
作者：He, Jin;Lu, Xuanqi;Mao, Ningning;Zhu, Tianyu;Yu, Lin;Yu, Yaming;Peng, Song;Deng, Xiangwen;Hu, Bing;Wang, Deyun;Lu, Yu;Jiang, Wenming
关键词：Oral vaccine; Dendritic fibrous nano-silica; Adjuvant; Mucosal and systemic immunity; cetyltrimethylammonium bromide (CTAB); triethanolamine (TEA); sodium salicylate (Nasal); tetraethoxysilane (TEOS); 3-aminopropyltriethoxysilane (APTES); 1-Ethyl-3-(3-dimethylaminopropyl); carbodiimide(EDC & sdot;HOL); N-Hydroxy succinimide (NHS); Lipopolysaccharide (LPS); phytohaemagglutinin (PHA); Cistanche deserticola polysaccharide (CDP)
