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A new nematicidal compound produced by Streptomyces albogriseolus HA10002

文献类型： 外文期刊

作者： Zeng, Qingfei 1 ; Huang, Huiqin 2 ; Zhu, Jun 2 ; Fang, Zhe 2 ; Sun, Qianguang 2 ; Bao, Shixiang 2 ;

作者机构： 1.Guizhou Inst Prataculture, Guiyang, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Trop Crop Biotechnol, Minist Agr, Haikou, Peoples R China

关键词： Bioactive compound;Nematicidal activity;Spectroscopic analyses;Streptomyces albogriseolus

期刊名称：ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY （ 影响因子：2.271； 五年影响因子：2.707 ）

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收录情况： SCI

摘要： Strain HA10002 was isolated from mangrove sediment collected from Dongzhaigang Mangrove Reserve in Hainan, China. It was selected with potent nematicidal activity and was identified as Streptomyces albogriseolus. By bioassay-guided fractionation, a new active component A22-1(S1) against root-knot nematodes was separated from its fermentation broth. On the basis of spectroscopic analyses and comparison with the data from correlative literature, the structure of S1 was established to be 6′-methyl-fungichromin, named as fungichromin B in this paper. The LD50 values of fungichromin B to the 2-stage juveniles of Meloidogyne incognita and Meloidogyne javanica were 7.64 and 7.83 μg/ml, respectively. Further examination demonstrated fungichromin B still showed a wide antifungal spectrum, as with fungichromin.

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