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A new flavanocoumarin from the root of Flemingia philippinensis

文献类型: 外文期刊

作者: Fu, Manqin 1 ; Deng, Dun 3 ; Huang, Riming 2 ; Zhang, Nenling 2 ; Su, Zhiwei 2 ; Qiu, Samuel X. 2 ;

作者机构: 1.Guangdong Acad Agr Sci, Guangdong Open Access Lab Agr Prod Proc, Sericulture & Farm Produce Proc Res Inst, Guangzhou 510610, Guangdong, Peoples R China

2.Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China

3.Anhui Sci & Technol Univ, Coll Life Sci, Fengyang 233100, Peoples R China

关键词: Flavanocoumarin;Flemingia philippinensis;Leguminosae

期刊名称:NATURAL PRODUCT RESEARCH ( 影响因子:2.861; 五年影响因子:2.572 )

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收录情况: SCI

摘要: One new flavanocoumarin, flemicoumarin A (1) was isolated from the EtOAc-soluble partition of the root of Flemingia philippinensis, along with three known compounds, namely 4,2′-epoxy-4′,5-dihydroxy-7,5′- dimethoxy-3-phenylcoumarin (2), kaempferol 6-C-glucoside (3) and dracocephaloside (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR, CD and MS data. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Compounds 1-4 exhibited inactivity against MCF-7, A549 and Hep-G2 human cancer cell lines in vitro by MTT colorimetric assay.

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