文献类型： 外文期刊
作者： Lv, Xiu-Qing 1 ; Feng, Gang 2 ; Liu, Ying-Qian 3 ; Nan, Xiang 3 ; Yang, Liu 4 ;
作者机构： 1.Jinzhong Univ, Coll Chem & Chem Engn, Jinzhong 030600, Peoples R China
2.Chinese Acad Trop Agr Sci, Environm & Plant Protect Inst, Danzhou 571737, Peoples R China
3.Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China
4.Lanzhou Jiaotong Univ, Environm & Municipal Engn Sch, Lanzhou 730000, Peoples R China
关键词： Combretastatin A-4;Spodoptera litura;Food intake;Larval growth;Mortality
期刊名称：MEDICINAL CHEMISTRY RESEARCH （ 影响因子：1.965； 五年影响因子：1.98 ）
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收录情况： SCI
摘要： The insecticidal activity of a natural compound combretastatin A-4 (CA-4) was assessed in in vivo assays against Spodoptera litura. CA-4, mixed into an artificial diet, caused various effects, depending on the concentration used. Compared with controls, food intake was lower, larval growth was reduced and larval development prolonged. Pupae weight was reduced, and adult morphology was also affected. Relative to the untreated group, treated groups showed higher mortality at larval and pupal stages, which was generally caused by moult disruption. Results of this study with CA-4 resemble those found in treatment with insect growth regulators. This study indicated that CA-4 merits further study as a lead compound in a novel class of potential insect-control agents or for managing field populations of Lepidoptera pests on cruciferous crops.
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