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Health risk assessment of Chinese consumers to nickel via dietary intake of foodstuffs

文献类型: 外文期刊

作者: Wang, Wen 1 ; Zhang, Zhiheng 1 ; Yang, Guiling 1 ; Wang, Qiang 1 ;

作者机构: 1.Zhejiang Acad Agr Sci, Inst Qual & Stand Agroprod, Hangzhou, Zhejiang, Peoples R China

2.Minist Agr, Lab Qual & Safety Risk Assessment Agroprod Hangzh, Hangzhou, Zhejiang, Peoples R China

3.State Key Lab Breeding Base Zhejiang Sustainable, Hangzhou, Zhejiang, Peoples R China

关键词: dietary exposure;China;nickel;health risk assessment;target hazard quotient

期刊名称:FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT ( 影响因子:3.057; 五年影响因子:2.96 )

ISSN:

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收录情况: SCI

摘要: A quantitative risk assessment was carried out to characterise the health risk from nickel (Ni) via dietary exposure for Chinese consumers. Ni contamination in foods was investigated by conducting a survey and a literature review. The daily diet of the public was categorised into nine food groups and the consumption data for each group were obtained from a nationwide survey. Deterministic and probabilistic methods were applied to calculate the target hazard quotients (THQs) by comparing the estimated dietary Ni intake with respect to the tolerable daily intake (TDI). The average estimated daily Ni intake (mu gkg(-1) bwday(-1)) for men, women, 2-3-year-old children and 4-17-year-old children were 7.2, 7.3, 17.1 and 10.0, respectively. The consumption of cereals, beans, vegetables and marine products contributed significantly to the total daily intake of Ni. The mean THQ values (95% confidence interval) and the probability of dietary Ni exposure higher than the TDI were 0.60 (0.58-0.62) and 8.2% for men, 0.61 (0.59-0.63) and 8.4% for women, 1.35 (1.32-1.39) and 72.0% for 2-3-year-old children, and 0.87 (0.82-0.91) and 28.5% for 4-17-year-old children, respectively. This study showed a potential health risk from Ni via dietary exposure for Chinese consumers, especially among children.

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