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Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp

文献类型： 外文期刊

作者： Huang, Fei 1 ; Guo, Yajuan 1 ; Zhang, Ruifen 2 ; Yi, Yang 3 ; Deng, Yuanyuan 2 ; Su, Dongxiao 1 ; Zhang, Mingwei 2 ;

作者机构： 1.Huazhong Agr Univ, Dept Food Sci & Technol, Wuhan 430070, Peoples R China

2.Guangdong Acad Agr Sci, Sericultural & Agri Food Res Inst, Guangzhou 510610, Guangdong, Peoples R China

3.Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Peoples R China

关键词： litchi pulp;polysaccharides;drying method;immunomodulatory activity

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

ISSN：

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收录情况： SCI

摘要： Dried litchi pulp has been used in traditional remedies in China for many years to treat various diseases, and the therapeutic activity has been, at least partly, attributed to the presence of bioactive polysaccharides. Polysaccharide-protein complexes from vacuum freeze-(VF), vacuum microwave-(VM) and heat pump (HP) dried litchi pulp, which were coded as LP-VF, LP-VM and LP-HP, were comparatively studied on the physicochemical and immunomodulatory properties. LP-HP had a predominance of galactose, while glucose was the major sugar component in LP-VF and LP-VM. Compared with LP-VF and LP-VM, LP-HP contained more aspartate and glutamic in binding protein. LP-HP also exhibited a stronger stimulatory effect on splenocyte proliferation at 200 mu g/mL and triggered higher NO, TNF-alpha and IL-6 secretion from RAW264.7 macrophages. Different drying methods caused the difference in physicochemical properties of polysaccharide-protein complexes from dried litchi pulp, which resulted in significantly different immunomodulatory activity. HP drying appears to be the best method for preparing litchi pulp to improve its immunomodulatory properties.

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[1]Characterization and mesenteric lymph node cells-mediated immunomodulatory activity of litchi pulp polysaccharide fractions. Huang, Fei,Zhang, Ruifen,Liu, Yang,Xiao, Juan,Su, Dongxiao,Wei, Zhencheng,Zhang, Mingwei,Yi, Yang,Wang, Guangjin.

[2]Comparison of Physicochemical Properties and Immunomodulatory Activity of Polysaccharides from Fresh and Dried Litchi Pulp. Huang, Fei,Su, Dongxiao,Huang, Fei,Zhang, Ruifen,Tang, Xiaojun,Zhang, Mingwei,Su, Dongxiao,Deng, Yuanyuan,Wei, Zhencheng,Yi, Yang.

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