您好,欢迎访问中国水产科学研究院 机构知识库!

Evaluation of tributyltin toxicity in Chinese rare minnow larvae by abnormal behavior, energy metabolism and endoplasmic reticulum stress

文献类型: 外文期刊

作者: Li, Zhi-Hua 1 ; Li, Ping 1 ;

作者机构: 1.Chinese Acad Fishery Sci, Key Lab Freshwater Biodivers Conservat, Key Field Stn Fishery Resource & Environm Upper M, Minist Agr,Yangtze River Fisheries Res Inst, Wuhan 430223, Peoples R China; Univ South Bohemia Ceske Budejovice, Fac Fisheries & Protect Waters, South Bohemian Res Ctr Aquaculture & Biodivers Hy, Res Inst Fish Culture & Hydrobiol, Vodnany 38925, Czech Republic

关键词: Fish;Tributyltin;Behavior;Energy metabolism;Endoplasmic reticulum stress

期刊名称:CHEMICO-BIOLOGICAL INTERACTIONS ( 影响因子:5.192; 五年影响因子:4.61 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Tributyltin (TBT) is a ubiquitous contaminant in aquatic environment, but the detailed mechanisms underlying the toxicity of TBT have not been fully understood. In this study, the effects of TBT on behavior, energy metabolism and endoplasmic reticulum (ER) stress were investigated by using Chinese rare minnow larvae. Fish larvae were exposed at sublethal concentrations of TBT (100, 400 and 800 ng/L) for 7 days. Compared with the control, energy metabolic parameters (RNA/DNA ratio, Na+-K+-ATPase) were significantly inhibited in fish exposed at highest concentration (800 ng/L), as well as abnormal behaviors observed. Moreover, we found that the PERK (PKR-like ER kinase) eIF2 alpha, (eukaryotic translation initiation factor 2 alpha) pathway, as the main branch was activated by TBT exposure in fish larvae. In short, TBT-induced physiological, biochemical and molecular responses in fish larvae were reflected in parameters measured in this study, which suggest that these biomarkers could be used as potential indicators for monitoring organotin compounds present in aquatic environment. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

  • 相关文献

[1]Alteration of cytochrome P450 1 regulation and HSP 70 level in brain of juvenile common carp (Cyprinus carpio) after chronic exposure to tributyltin. Li, Zhi-Hua,Zhong, Li-Qiao,Wu, Yan-Hua,Mu, Wei-Na,Li, Zhi-Hua,Wu, Yan-Hua,Mu, Wei-Na.

[2]Effects of chronic exposure to tributyltin on tissue-specific cytochrome P450 1 regulation in juvenile common carp. Li, Zhi-Hua,Zhong, Li-Qiao,Mu, Wei-Na,Wu, Yan-Hua,Li, Zhi-Hua,Mu, Wei-Na,Wu, Yan-Hua.

[3]Activating nuclear xenobiotic receptors and triggering ER stress and hepatic cytochromes P450 systems in quails (Coturnix C-coturnix) during atrazine exposure. Du, Zheng-Hai,Qin, Lei,Lin, Jia,Xia, Jun,Zhang, Cong,Li, Xue-Nan,Li, Jin-Long,Qin, Lei,Sun, Yan-Chun,Zhang, Cong,Li, Xue-Nan,Li, Jin-Long.

[4]Transplacental transfer of butyltins to fetus of Dall's porpoises (Phocoenoides dalli). Yang, Jian,Miyazaki, Nobuyuki.

[5]Effect of bis(tributyltin) oxide on reproduction and population growth rate of calanoid copepod Schmackeria poplesia. Huang Ying,Zhu Liyan,Qiu Xuchun,Zhang Tianwen,Huang Ying,Huang Ying. 2010

[6]Metabolism of tributyltin and triphenyltin by Dall's porpoise hepatic microsomes. Yang, Jian,Oshima, Yuji,Sei, Ito,Miyazaki, Nobuyuki.

[7]Trace elements and butyltins in a Dall's porpoise (Phocoenoides dalli) from the Sanriku coast of Japan. Yang, J,Miyazaki, N,Kunito, T,Tanabe, S.

[8]Physiological and molecular responses in brain of juvenile common carp (Cyprinus carpio) following exposure to tributyltin. Li, Zhi-Hua,Li, Ping,Shi, Ze-Chao,Li, Zhi-Hua,Li, Ping.

[9]Physiological Responses in Chinese Rare Minnow Larvae Following Exposure to Low-Dose Tributyltin. Li, Ping,Li, Zhi-Hua,Li, Ping,Li, Zhi-Hua.

[10]Toxicity of Tributyltin in Juvenile Common Carp (Cyprinus Carpio): Physiological Responses, Hepatic Gene Expression, and Stress Protein Profiling. Li, Zhi-Hua,Zhong, Li-Qiao,Mu, Wei-Na,Wu, Yan-Hua,Li, Zhi-Hua,Mu, Wei-Na,Wu, Yan-Hua.

[11]Effects of Temperature on Biogenic Amine Production of Four Popular Fish Species Sold in Southern China. Yang Xianqing,Zhai Honglei,Li Laihao,Hao Shuxian,Cen Jianwei,Qi Bo,Xia Guobin. 2012

[12]Information System of Fish Germplasm Resources in China. Yang Ningsheng,Ge Chanshui,Ouyang Haiying. 2002

[13]The detrimental effects of CO2-driven chronic acidification on juvenile Pacific abalone (Haliotis discus hannai). Li, Jiaqi,Mao, Yuze,Jiang, Zengjie,Zhang, Jihong,Fang, Jianguang,Li, Jiaqi,Mao, Yuze,Jiang, Zengjie,Zhang, Jihong,Fang, Jianguang,Bian, Dapeng. 2018

[14]Anesthesia and Recovery with Clove Oil in Juvenile Siberian Sturgeon (Acipenser baerii). Guangpeng Feng,Jianyi Liu,Ping Zhuang,Longzhen Zhang,Ming Duan. 2011

[15]The Efficacy of MS-222 as an Anesthetic for Juvenile Siberian Sturgeon (Acipenser baerii Brandt 1869). Guangpeng Feng,Ping Zhuang,Jianyi Liu,Longzhen Zhang,Tao Zhang. 2011

[16]Nonisothermal crystallization kinetics of poly(ethylene terephthalate)/antimony-doped tin oxide nanocomposites. Chen, Xiaolei,Li, Chunzhong,Shao, Wei,Chen, Xiaolei,Wang, Lumin,Liu, Tianxi.

[17]1-Deoxynojirimycin from Bacillus subtilis improves antioxidant and antibacterial activities of juvenile Yoshitomi tilapia. Tang, Lining,Huang, Kai,Sun, Lei,Huang, Qing,Bi, Yanjun,Xie, Jun,Yu, Dan. 2017

[18]Physiological responses and gene expression changes in the western mosquitofish (Gambusia affinis) exposed to progesterone at environmentally relevant concentrations. Hou, Liping,Yang, Yang,Shu, Hu,Cheng, Xuemei,Xu, Hongyan,Ying, Guangguo,Zhao, Jianliang,Ying, Guangguo,Zhao, Jianliang. 2017

[19]Metals in the Tissues of Two Fish Species from the Rare and Endemic Fish Nature Reserve in the Upper Reaches of the Yangtze River, China. Cai, Shenwen,Ni, Zhaohui,Li, Yunfeng,Shen, Ziwei,Zhang, Yan,Zhou, Yuntao,Cai, Shenwen,Xiong, Zhiting. 2012

[20]Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost, oncorhynchus mykiss: a comparative study of in vivo and in vitro. Li, Zhi-Hua,Li, Ping,Randak, Tomas,Li, Zhi-Hua,Li, Ping. 2011

作者其他论文 更多>>