您好，欢迎访问江苏省农业科学院 机构知识库！
江苏省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Characterization of a novel polysaccharide with anti-colon cancer activity from Lactobacillus helveticus MB2-1

文献类型： 外文期刊

作者： Li, Wei 1 ; Tang, Weizhi 1 ; Ji, Juan 1 ; Xia, Xiudong 2 ; Rui, Xin 1 ; Chen, Xiaohong 1 ; Jiang, Mei 1 ; Zhou, Jianzhong 2 ;

作者机构： 1.Nanjing Agri cultural Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China

2.Jiangsu Acad Agr Sci, Inst Agroprod Proc, Nanjing 210095, Jiangsu, Peoples R China

关键词： Lactobacillus helveticus MB2-1;Exopolysaccharides;Anti-colon cancer activity;Structural characterization;Methylated analysis;Nuclear magnetic resonance spectroscopy

期刊名称：CARBOHYDRATE RESEARCH （ 影响因子：2.104； 五年影响因子：2.192 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The present study aimed at investigating the potential anti-colon cancer activity of three purified exopolysaccharides fractions (LHEPS-1, LHEPS-2 and LHEPS-3) from the Lactobacillus helveticus MB2-1. The experimental evidence showed that LHEPS-1 significantly inhibited cell proliferation of human colon cancer Caco-2 cells in both time-and concentration-dependent manners. In contrast, no significant improvements of the inhibitory effects of LHEPS-2 and LHEPS-3 on Caco-2 cells were observed with increasing sample concentrations or prolonged incubation time. Furthermore, the structure of LHEPS-1 was elucidated using methylated analysis, gas chromatography-mass spectroscopy (GC-MS) and nuclear magnetic resonance spectroscopy (NMR), including one-and two-dimensional nuclear magnetic resonance (1D and 2D NMR). Results indicated that the LHEPS-1 consisted of a decasaccharide repeating unit with the following structure (n approximate to 122):

  • 相关文献

[1]Structural Characterization and Anticancer Activity of Cell-Bound Exopolysaccharide from Lactobacillus helveticus MB2-1. Li, Wei,Tang, Weizhi,Ji, Juan,Rui, Xin,Chen, Xiaohong,Jiang, Mei,Zhang, Qiuqin,Dong, Mingsheng,Xia, Xiudong,Zhou, Jianzhong.

[2]Characterization of hemicelluloses from Neolamarckia cadamba (Rubiaceae) during xylogenesis. Zhao, Xianhai,Tong, Tingting,Chen, Xiaoyang,Wu, Ai-Min,Zhao, Xianhai,Tong, Tingting,Wu, Ai-Min,Zhao, Xianhai,Tong, Tingting,Li, HuiLing,Lu, Haojun,Deng, Xiaomei,Chen, Xiaoyang,Wu, Ai-Min,Zhao, Xianhai,Tong, Tingting,Li, HuiLing,Lu, Haojun,Deng, Xiaomei,Chen, Xiaoyang,Wu, Ai-Min,Ren, Junli,Zhang, Aiping.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：江苏省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台