Synthesis, Biological Evaluation, and Structure-Activity Relationship Study of Novel Stilbene Derivatives as Potential Fungicidal Agents
文献类型： 外文期刊
作者： He, Daohang 1 ; Jian, Weilin 1 ; Liu, Xianping 1 ; Shen, Huifang 2 ; Song, Shaoyun 3 ;
作者机构： 1.S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China
2.Guangdong Acad Agr Sci, Plant Protect Res Inst, Guangzhou 510640, Guangdong, Peoples R China
3.Sun Yat Sen Univ, State Key Lab Biocontrol, Guangzhou 510006, Guangdong, Peoples R China
关键词： stilbene derivatives;1;3;4-oxadiazole;3D-QSAR;fungicidal activity;synthesis
期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.279； 五年影响因子：5.269 ）
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收录情况： SCI
摘要：
A total of 22 novel stilbene derivatives containing the 1,3,4-oxadiazole moiety and trimethoxybenzene were designed and synthesized. Their chemical structures were characterized by H-1 and C-13 nuclear magnetic resonance, infrared, and high-resolution mass spectrometry. Bioassay results revealed that some of the title compounds showed potent in vivo fungicidal activities against three phytopathogenic fungi (Pseudoperonospora cubensis, Colletotrichum lagenarium, and Septoria cucurbitacearum) from cucurbits at 600 mu g/mL. Notably, compounds
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