Tuning the mechanical and morphological properties of self-assembled peptide hydrogels via control over the gelation mechanism through regulation of ionic strength and the rate of pH change
文献类型： 外文期刊
作者： Li, Rui 1 ; Horgan, Conor C. 2 ; Long, Benjamin 1 ; Rodriguez, Alexandra L. 2 ; Mather, Lauren 1 ; Barrow, Colin J. 1 ;
作者机构： 1.Deakin Univ, Sch Life & Environm Sci, Ctr Chem & Biotechnol, Waurn Ponds, Vic 3216, Australia
2.Australian Natl Univ, Res Sch Engn, Canberra, ACT 2601, Australia
3.Chinese Acad Trop Agr Sci, Coconut Res Inst, Wenchang 571339, Hainan, Peoples R China
4.RMIT Univ, Sch Aerosp Mech & Mfg Engn, Bundoora, Vic 3083, Australia
期刊名称：RSC ADVANCES （ 影响因子：3.361； 五年影响因子：3.39 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Hydrogels formed by the self-assembly of peptides are promising biomaterials. The bioactive and biocompatible molecule Fmoc-FRGDF has been shown to be an efficient hydrogelator via a pi-beta self-assembly mechanism. Herein, we show that the mechanical properties and morphology of Fmoc-FRGDF hydrogels can be effectively and easily manipulated by tuning both the final ionic strength and the rate of pH change. The increase of ionic strength, and consequent increase in rate of gelation and stiffness, does not interfere with the underlying pi-beta assembly of this Fmoc-protected peptide. However, by tuning the changing rate of the system's pH through the use of glucono-delta-lactone to forma hydrogel, as opposed to the previously reported HCl methodology, the morphology (nano- and microscale) of the scaffold can be manipulated.
- 相关文献
作者其他论文 更多>>
-
Glutathione triggers leaf-to-leaf, calcium-based plant defense signaling
作者：Li, Rui;Yang, Yongfang;Lou, Hao;Wang, Weicheng;Du, Xiaoxi;Hu, Shuai;Shan, Xiaoyi;Xie, Daoxin;Li, Rui;Yang, Yongfang;Lou, Hao;Wang, Weicheng;Du, Xiaoxi;Hu, Shuai;Wang, Guo-Liang;Shan, Xiaoyi;Xie, Daoxin;Li, Rui;Du, Ran;Chen, Haidong;Yan, Jianbin;Yang, Yongfang;Du, Xiaoxi;Hu, Shuai;Du, Xiaoxi;Hu, Shuai;Wang, Guo-Liang;Xie, Daoxin
关键词：
-
Integrated transcriptomic and metabolomic analyses uncover differential regulation of oleic acid synthesis in oil palm varieties with different shell types
作者：Xu, Wen;Li, Xinyu;Martin, Jerome Jeyakumar John;Song, Fei;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Ye, Jianqiu;Cao, Hongxing;Xu, Wen;Li, Xinyu;Martin, Jerome Jeyakumar John;Song, Fei;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Ye, Jianqiu;Cao, Hongxing;Xu, Wen
关键词：Oil palm; Oleic acid biosynthesis; Differential mechanisms; Transcriptome; Metabolite
-
Multi-omic analysis to develop key genes involved in carotenoid synthesis and establish indicative molecular markers for oil palm fruit colour
作者：Zhang, Ruimin;Liu, Xiaoyu;Cheng, Yang;Martin, Jerome Jeyakumar John;Li, Xinyu;Zhou, Lixia;Fu, Dengqiang;Li, Qihong;Li, Rui;Cao, Hongxing;Zhang, Ruimin;Liu, Xiaoyu;Cheng, Yang;Martin, Jerome Jeyakumar John;Li, Xinyu;Zhou, Lixia;Fu, Dengqiang;Li, Qihong;Li, Rui;Cao, Hongxing;Cheng, Yang
关键词：oil palm; nigrescens; virescens; Metabolome; Transcriptome; Carotenoids; Kompetitive Allele-Specific PCR molecular; marker
-
Interaction of R2R3-MYB transcription factor EgMYB111 with ABA receptors enhances cold tolerance in oil palm
作者：Zhou, Lixia;Li, Rui;Yang, Xuanwen;Yang, Yaodong;Zhou, Yongfeng;Zhou, Lixia;Li, Rui;Yang, Yaodong;Iqbal, Amjad;Yang, Xuanwen;Peng, Yanling;Wang, Yiwen;Xu, Qi;Su, Xiangnian;Zhou, Yongfeng;Wang, Yiwen;Iqbal, Amjad
关键词：Elaeis guineensis; Oil palm; MYB transcription factors; EgMYB111; ABA signaling pathway; Cold tolerance
-
Deciphering the molecular mechanisms of oil palm lipid metabolism through combined metabolomics and transcriptomics☆
作者：Martin, Jerome Jeyakumar John;Xu, Wen;Li, Xinyu;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Cao, Hongxing;Martin, Jerome Jeyakumar John;Xu, Wen;Li, Xinyu;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Cao, Hongxing;Xu, Wen
关键词：Oil palm; Lipid biosynthesis; Metabolomics; Transcriptomics; Lipid metabolism; Fatty acid; Genetic improvement
-
Fatty Acid and Lipid Metabolism in Oil Palm: From Biochemistry to Molecular Mechanisms
作者：Afifi, Eman H.;Martin, Jerome Jeyakumar John;Wang, Qi;Li, Xinyu;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Ye, Jianqiu;Cao, Hongxing;Afifi, Eman H.;Martin, Jerome Jeyakumar John;Wang, Qi;Li, Xinyu;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Ye, Jianqiu;Cao, Hongxing;Afifi, Eman H.
关键词：oil palm; fatty acid metabolism; lipid biosynthesis; lipid accumulation; biochemical pathways; molecular mechanisms
-
Joint analysis of transcriptional metabolism for flavonoid synthesis during different developmental periods in oil palm exocarp
作者：Zhang, Ruimin;Zhang, Ruimin;Martin, Jerome Jeyakumar John;Liu, Xiaoyu;Li, Xinyu;Zhou, Lixia;Li, Rui;Fu, Xiaopeng;Cao, Hongxing;Li, Wenrao
关键词：oil palm; metabolomics; transcriptomics; flavonoids; biosynthesis
