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ADDITIVE TOXICITIES OF ANILINES, NITROBENZENES, PHENOLS, AND PHTHALATES ON PHOTOBACTERIUM Q67

文献类型: 外文期刊

作者: Ge, Huilin 1 ; Mo, Lingyun 2 ; Zhu, Zhu 3 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Hainan Key Lab Qual & Safety Trop Fruit & Vegetab, Anal & Testing Ctr, Haikou 571101, Peoples R China

2.Guilin Univ Technol, Coll Chem & Bioengn, Guilin 541004, Peoples R China

3.Hainan Univ, Coll Environm & Plant Protect, Haikou 570228, Peoples R China

关键词: Concentration addition;independent action;uniform design;microplate toxicity analysis;Vibrio qinghaiensis

期刊名称:FRESENIUS ENVIRONMENTAL BULLETIN ( 影响因子:0.489; 五年影响因子:0.479 )

ISSN:

年卷期:

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收录情况: SCI

摘要: The effects of four anilines, two nitrobenzenes, four phenols, two phthalates individually, and their mixtures on the bioluminescence inhibition of Vibrio qinghaiensis sp.-Q67 were studied by using microplate toxicity analysis. The toxicity of a substituted benzene will increase when introducing -NO2, -NH2, or -CH3 into the molecule. The mixtures of these substituted benzenes were built according to uniform design concentration ratio method. The pEC(50) of mixtures had a monotonically increasing relationship with the concentration proportion of the component having the most toxicity in the mixtures. Observed mixture toxicities were compared with predictions calculated by concentration addition (CA) and independent action (IA) models. CA and IA made equally good predictions for the mixture toxicities, irrespective of mixture ratios and effect levels. The mixture of the anilines, nitrobenzenes, phenols, and phthalates presented additive toxicity on photobacterium Q67.

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