One-step synthesis of fluorescent silicon quantum dots (Si-QDs) and their application for cell imaging
文献类型： 外文期刊
作者： Wu, Jinzhu 1 ; Dai, Jun 1 ; Shao, Yanbin 2 ; Sun, Yanchun 3 ;
作者机构： 1.Harbin Inst Technol, Sch Sci, Dept Chem, Harbin 150001, Peoples R China
2.Harbin Inst Technol, Acad Fundamental & Interdisciplinary Sci, Harbin 150001, Peoples R China
3.Chinese Acad Fishery Sci, Heilongjiang River Fishery Res Inst, Harbin 150001, Peoples R China
期刊名称：RSC ADVANCES （ 影响因子：3.361； 五年影响因子：3.39 ）
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收录情况： SCI
摘要： Novel fluorescent silicon quantum dots (Si-QDs) were synthesized by a one-step hydrothermal procedure using (3-aminopropyl) trimethoxysilane (APTES) as a silicon source and sodium ascorbate (SA) as a reducing agent. This synthetic strategy is straightforward, efficacious and low-cost. The as-synthesized Si-QDs featured narrow size distribution, intense purple-blue fluorescence with a photoluminescence quantum yield (PL QY) of 21%, complete water solubility, and favorable biocompatibility. Moreover, the resultant Si-QDs present robust stability in different circumstances, such as for long-term storage in air, in a wide pH range of 2-12 and under continuous UV irradiation, and they also do not respond to some metal ions. Their superior stability and safety render Si-QDs applicable as fluorescent probes in biomedical applications. The use of Si-QDs as an optical probe is illustrated by fluorescent imaging of IE8 cells.
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