Genome-wide association study of 8 carcass traits in Jinghai Yellow chickens using specific-locus amplified fragment sequencing technology
文献类型： 外文期刊
作者： Wang, Wenhao 1 ; Zhang, Tao 1 ; Wang, Jinyu 1 ; Zhang, Genxi 1 ; Wang, Yongjuan 3 ; Zhang, Yinwen 4 ; Zhang, Jianhui 4 ;
作者机构： 1.Yangzhou Univ, Dept Anim Sci, Yangzhou 225009, Jiangsu, Peoples R China
2.Yichun Univ, Dept Life Sci Resources & Environm, Yichun 336000, Peoples R China
3.JiangsuJinghai Poultry Ind Grp CD LTD, Nantong 226000, Peoples R China
4.Biomarker Technol Corp, Beijing 100000, Peoples R China
5.Heilongjiang Acad Agr Sci, Anim Husb Res Inst, Harbin 150086, Peoples R China
关键词： Carcass trait;chicken;GWAS;SLAF-seq
期刊名称：POULTRY SCIENCE （ 影响因子：3.352； 五年影响因子：3.679 ）
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收录情况： SCI
摘要： Carcass traits are important to the commercial chicken industry, and understanding the genetics of these traits will be useful in the development of commercially viable varieties of chickens. We conducted a genome-wide association study based on 8 carcass trait phenotypes in a population of 400 43-week- old Jinghai Yellow chickens. Specific-locus amplified fragment sequencing technology was used to identify 90,961 single nucleotide polymorphisms (SNP) distributed among 29 chromosomes and the mitochondrial genome. SNP that were significantly associated with phenotypic traits were identified by a simple general linear model. Fifteen SNP attained genome-wide significance (P < 1.87E-6) and were associated with 5 of the 8 carcass traits; only one SNP was significantly associated with 2 traits (foot weight and wing weight). Twelve genes were associated with these 15 SNP. A region of chromosome 4 between 75.5 and 76.1 Mb was associated with carcass weight, foot weight, and wing weight. An 84-kb region on chromosome 3 (51.2 Mb) was associated with eviscerated weight and semi-eviscerated weight.
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