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Cumulative risk assessment of the exposure to pyrethroids through fruits consumption in China - Based on a 3-year investigation

文献类型： 外文期刊

作者： Li, Zhixia 1 ; Nie, Jiyun 1 ; Lu, Zeqi 3 ; Xie, Hanzhong 4 ; Kang, Lu 5 ; Chen, Qiusheng 6 ; Li, An 7 ; Zhao, Xubo 8 ; Xu, G 1 ;

作者机构： 1.Chinese Acad Agr Sci, Inst Pomol, Xingcheng 125100, Peoples R China

2.Minist Agr, Lab Qual & Safety Risk Assessment Fruit Xingchen, Xingcheng, Peoples R China

3.Yantai Acad Agr Sci, Yantai, Peoples R China

4.Chinese Acad Agr Sci, Zhengzhou Inst Pomol, Zhengzhou 450009, Peoples R China

5.Xinjiang Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Urumqi 830091, Peoples R China

6.Inst Tianjin Agr Qual Standard & Testing Technol, Tianjin 300381, Peoples R China

7.Beijing Res Ctr Agr Stand & Testing, Beijing 100097, Peoples R China

8.Northwest A

关键词： Cumulative dietary exposure;Pyrethroid residue;Deterministic assessment;Semi-probabilistic assessment;Fruits

期刊名称：FOOD AND CHEMICAL TOXICOLOGY （ 影响因子：6.023； 五年影响因子：5.844 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： In the present study, the long-term and short-term cumulative risks of pyrethroids exposured for the Chinese general population and children through fruits consumption were evaluated. A total of 1450 fruit samples and seven pyrethroids were included based on the pesticide residues monitoring programme of China from 2013 to 2015. The exposure was estimated using both deterministic approach and semi probabilistic model for comparison. The hazard index approach was used to assess cumulative risk. 26% of samples contained pyrethroid residues with concentrations ranged from 0.0050 mg/kg to 1.2 mg/kg, of which 30% simultaneously with 2-4 mixture residues. Results demonstrated that the cumulative health risks were extremely low for both general population and children (1-6 years old) of China in the long term. Acute risk estimations calculated by deterministic method were several or many times overestimated than the results based on semi-probabilistic method. Acute cumulative exposure of children to pyrethroid compounds in 0.76% samples were exceeded 1 in worst case scenario. More detailed assessments with adequate data in the future use probabilistic method is expected to reduce the uncertainties of cumulative dietary exposure. (C) 2016 Elsevier Ltd. All rights reserved.

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