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A highly sensitive and selective turn-on fluorescent probe for sulfite and its application in biological imaging

文献类型: 外文期刊

作者: Song, Jianhua 1 ; Zhang, Di 1 ; Liu, Yaqi 1 ; Zhao, Yufen 1 ; Ye, Yong 1 ;

作者机构: 1.Zhengzhou Univ, Phosphorus Chem Engn Res Ctr Henan Prov, Coll Chem & Mol Engn, Zhengzhou 450052, Peoples R China

2.Henan Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Zhengzhou, Peoples R China

3.Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China

期刊名称:NEW JOURNAL OF CHEMISTRY ( 影响因子:3.591; 五年影响因子:3.385 )

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收录情况: SCI

摘要: A turn-on fluorescein-based probe (1) has been successfully developed for the highly sensitive and selective detection of sulfite. The probe exhibits high SO32- selectivity over other common anions and biothiols (Cys, Hcy and GSH), and the detection limit was measured to be 0.55 mu M. Probe 1 exhibited high selectivity towards SO32- with a broad pH (4-9). A significant change from colorless to yellow could be directly observed by the naked eye. Furthermore, living cell imaging results demonstrated its practical application value in biological systems.

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