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A new rosamine-based fluorescent chemodosimeter for hydrogen sulfide and its bioimaging in live cells

文献类型: 外文期刊

作者: Cheng, Junye 1 ; Song, Jianhua 1 ; Niu, Huawei 1 ; Tang, Jun 1 ; Zhang, Di 2 ; Zhao, Yufen 1 ; Ye, Yong 1 ;

作者机构: 1.Zhengzhou Univ, Coll Chem & Mol Engn, Phosphorus Chem Engn Res Ctr Henan Prov, Zhengzhou, Peoples R China

2.Henan Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Zhengzhou, Peoples R China

3.Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing, Peoples R China

期刊名称:NEW JOURNAL OF CHEMISTRY ( 影响因子:3.591; 五年影响因子:3.385 )

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收录情况: SCI

摘要: A new probe ( RosN(3)), which displayed excellent selectivity to H2S in mixed aqueous media, was synthesized. This method employed the H2S-mediated reduction of azides to amines, resulting in fluorescence quenching. The probe exhibited high H2S selectivity over other common anions and biothiols. The detection limit was measured to be 0.25 mu M. Furthermore, the live cell imaging results demonstrated its potential for practical application in biological systems.

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