文献类型： 外文期刊
作者： Dong, Ji-lin 1 ; Zhu, Ying-ying 3 ; Ma, Yu-ling 1 ; Xiang, Qi-sen 1 ; Shen, Rui-ling 1 ; Liu, Yan-qi 1 ;
作者机构： 1.Zhengzhou Univ Light Ind, Sch Food & Biol Engn, 166 Kexue Rd, Zhengzhou 450002, Henan, Peoples R China
2.Zhengzhou Univ Light Ind, Collaborat Innovat Ctr Food Prod & Safety, 166 Kexue Rd, Zhengzhou 450002, Henan, Peoples R China
3.Univ Liege, Gembloux Agrobio Tech, Anim Sci Unit, Passage Deportes 2, B-5030 Gembloux, Belgium
4.Chinese Acad Agr Sci, Inst Crop Sci, 80 South Xueyuan Rd, Beijing 100081, Peoples R China
关键词： Oat products;Anti-obesity;TNF-alpha;Gut microflora;SCFA
期刊名称：JOURNAL OF FUNCTIONAL FOODS （ 影响因子：4.451； 五年影响因子：4.907 ）
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收录情况： SCI
摘要： Three oat products were supplemented into high fat diets and fed to obese rats for 8 weeks. Each oat product decreased body weight, epididymal fat accumulation, and serum inflammatory factor levels and significantly regulated serum lipid levels. Oat bran significantly reduced mean adipocyte size and TNF-alpha mRNA expression levels. Principal components analysis showed that the oat products shifted the overall structure of gut microbiota in DIO rats. The relative abundances of Bacteroidetes and Firmicutes and the Bacteroidetes/Firmicutes ratio were altered towards that of normal rats. Spearman's correlation analysis showed that changes in the overall microbiota composition were significantly correlated with total cholesterol, triacylglycerol, endotoxin, and tumour cell necrosis factor-alpha levels in serum, and mRNA expression levels. Oat products significantly increased the total short-chain fatty acids (SCFA) concentration in colonic digesta. These results suggest that oat products attenuate obesity and related metabolic disorders while modifying the gut microbiota composition in high fat diet-induced obese rats. (C) 2016 Elsevier Ltd. All rights reserved.
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