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Antioxidant, antibacterial and anti-aging activities of intracellular zinc polysaccharides from Grifola frondosa SH-05

文献类型： 外文期刊

作者： Zhang, Chen 1 ; Gao, Zheng 2 ; Hu, Chunlong 3 ; Zhang, Jianjun 2 ; Sun, Xinyi 2 ; Rong, Chengbo 1 ; Jia, Le 2 ;

作者机构： 1.Beijing Acad Agr & Forestry Sci, Beijing Engn Res Ctr Edible Mushroom, Inst Plant & Environm Protect, Key Lab Urban Agr North,Minist Agr, Beijing, Peoples R China

2.Shandong Agr Univ, Coll Life Sci, Tai An 271018, Shandong, Peoples R China

3.Shandong Agr Univ, Coll Forestry, Tai An 271018, Shandong, Peoples R China

关键词： Antioxidant and anti-aging activities;Histopathology assay;Antibacterial activities;Grifola frondosa SH-05;Intracellular zinc polysaccharides

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：6.953； 五年影响因子：6.737 ）

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收录情况： SCI

摘要： In present work, the strain of Grifola frondosa SH-05 was used as a vector of zinc biotransformation to produce the IZPS. The bioactivities including antioxidant and antibacterial activities in vitro and anti aging properties in vivo of IZPS were investigated comparing with the IFS. The results which were in consistent with the results of histopathology assay demonstrated that the IZPS had superior antioxidant and anti-aging activities by scavenging the hydroxyl and DPPH radicals, increasing enzyme activities, decreasing the MDA contents and ameliorating the anile condition of mice. Besides, the IZPS also showed potential antibacterial activities. The IZPS with higher bioactivities was composed of were Rha, 'no and Glu with a molar ratio of 4.7:3.6:1. These conclusions indicated that the IZPS might be a potential source of natural antioxidant, antibacterial agent and anti-aging agent. (C) 2016 Elsevier B.V. All rights reserved.

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