文献类型： 外文期刊
作者： Zhai, Jun-Qiong 1 ; Zhai, Shao-Lun; Lin, Tao; Liu, Jian-Kui 1 ; Wang, He-Xing; Li, Bing 1 ; Zhang, He 1 ; Zou, S 1 ;
作者机构： 1.South China Agr Univ, Key Lab Zoonosis Prevent & Control Guangdong Prov, Coll Vet Med, Guangzhou 510642, Guangdong, Peoples R China
2.South China Agr Univ, Key Lab Zoonosis Prevent & Control Guangdong Prov, Coll Vet Med, Guangz
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
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收录情况： SCI
摘要： Parainfluenza virus 5 (PIV5) is widespread in mammals and humans. Up to now, there is little information about PIV5 infection in lesser pandas. In this study, a PIV5 variant (named ZJQ-221) was isolated from a lesser panda with respiratory disease in Guangzhou zoo in Guangdong province, southern China. The full-length genome of ZJQ-221 was found to be 15,246 nucleotides and consisted of seven non-overlapping genes encoding eight proteins (i.e., NP, V, P, M, F, SH, HN and L). Sequence alignment and genetic analysis revealed that ZJQ-221 shared a close relationship with a PIV5 strain of canine-origin (1168-1) from South Korea. The findings of this study confirm the presence of PIV5 in lesser panda and indicate this mammal as a possible natural reservoir. Furthermore they highlight the urgent need to strengthen viral surveillance and control of PIV5 in zoo animals.
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