Effect of methomyl on sex steroid hormone and vitellogenin levels in serum of male tilapia (Oreochromis niloticus) and recovery pattern
文献类型: 外文期刊
作者: Meng, Shun-Long 1 ; Qiu, Li-Ping 2 ; Hu, Geng-Dong 2 ; Fan, Li-Min 2 ; Song, Chao 3 ; Zheng, Yao; Wu, Wei; Qu, Jian 1 ;
作者机构: 1.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Lab Qual & Safety Risk Assessment Aquat Prod Envi, Beijing, Peoples R China
2.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Lab Qual & Safety Risk Assessment Aquat Prod Envi, Beijing, Peoples R China; CAFS, Key Lab Fishery Ecoenvironm Assessment & Resource, Wuxi 214081, Peoples R China
3.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Lab Qual & Safety Risk Assessment Aquat Prod Envi, Beijing, Peoples R China; CAFS, Key Lab Fishery Ecoenvironm Asse
关键词: methomyl;recovery pattern;serum;sex steroid hormone;tilapia
期刊名称:ENVIRONMENTAL TOXICOLOGY ( 影响因子:4.119; 五年影响因子:3.404 )
ISSN:
年卷期:
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收录情况: SCI
摘要: Tilapia were exposed to sub-lethal concentrations of 0, 0.2, 2, 20 or 200 g/L for 30 days, then transferred to methomyl-free water for 18 days. E-2, T, 11-KTand VTG in serum were examined. There were no significant changes in all the parameters in serum of tilapia exposed to 0.2 g/L and 2 g/L methomyl compared to the control. However, 20 g/L and 200 g/L have the potential to disrupt the endocrine system of male tilapia, as shown by its ability to increase VTG and E-2 and decrease T and 11-KT in serum. Thus it would appear the no observed adverse effect level for sexual steroid hormones of methomyl is lower than 2 g/L. Recovery data showed that the effects produced by 20g/L were reversible but not at 200g/L. Furthermore, the sensitivity of above parameters to methomyl followed the order of VTG>E-2>11-KT>T>GSI, suggesting VTG being the better biomarkers.
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