Paired box 7 (Pax7) gene: molecular characterisation, polymorphism and its association with growth performance in goose (Anser cygnoides)
文献类型： 外文期刊
作者： Wang, C. 1 ; Yang, Y. Z. 1 ; Liu, Y. 1 ; Gong, S. M. 1 ; Wang, H. Y. 1 ; He, D. Q. 1 ;
作者机构： 1.Shanghai Acad Agr Sci, Inst Anim Husb & Vet Sci, Shanghai, Peoples R China
关键词： Body weight;cloning;Pax7;SNPs;Zhedong-White goose
期刊名称：BRITISH POULTRY SCIENCE （ 影响因子：2.095； 五年影响因子：2.266 ）
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收录情况： SCI
摘要： 1. Paired box (Pax7) gene is a member of the paired box family and plays a critical role in animal growth and muscle development. However, the molecular characterisation of the goose Pax7 gene is unknown.2. The open-reading frame of goose Pax7 is composed of 1509bp, which encodes a protein of 503 amino acids and shares high homology with Pax7 of other birds.3. Ten single-nucleotide polymorphisms were identified in the genomic DNA sequence, 8 located in the intron region and two located in the exon region.4. Association analysis showed the C122T locus was significantly associated with the body weight of Zhedong-White geese in week 4, 6, 8, 10 and 12.5. It was concluded that the goose Pax7 gene may be an important candidate gene for goose growth traits and marker-assisted selection.
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